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4-aminopyridine

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Origem: China

Cas No: 504-24-5

Especificação: 99%Min

Quantidade de ordem min: 1 /kg

Capacidade de fornecimento: 50 mt/month

Tempo de espera: 7 dias para OEM, 3 dias para produtos prontos

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Descrição do produto

Quick Details
CAS No.:
504-24-5
Other Names:
4-Aminopyridine
MF:
C5H6N2
EINECS No.:
207-987-9
Place of Origin:
Shandong, China
Type:
Pharmaceutical Intermediates
Purity:
99%.
Brand Name:
bosschemical
Model Number:
RTS: 504-24-5
Application:
organic intermediates
Appearance:
powder
Product name:
4-Aminopyridine
Description:
powder
CAS:
504-24-5
Molecular Formula:
C5H6N2
EINECS:
207-987-9
Molecular weight:
94.11
Brands:
bosschemical
Assay:
99%.
usage:
Chemical reagent
Package:
Aluminum foil bag, vial bottle, fluorinated bottle
Packaging&Delivery
Selling Units:
Multiple of 5
Package size per batch:
1X1X1 cm
Gross weight per batch:
0.009 kg
Package Type:
```
Aluminum foil bag, vial bottle, fluorinated bottle
```
Lead Time:
Quantity(Grams) 1 - 5000 >5000
Est. Time(days) 10 To be negotiated

Property

CAS No.: 504-24-5 Formula: C5H6N2 Molecular Weight: 94.11450

Description

4-Aminopyridine (4-AP, INN fampridine, USAN dalfampridine) is an organic compound with the chemical formula C5H4N–NH2. The molecule is one of the three isomeric amines of pyridine. It is used as a research tool, in characterizing subtypes of the potassium channel. It has also been used as a drug, to manage some of the symptoms of multiple sclerosis, and is indicated for symptomatic improvement of walking in adults with several variations of the disease. It was undergoing PhaseIII clinical trials as of 2008[update], and the U.S. Food and Drug Administration (FDA) approved the compound on January 22, 2010. Fampridine is also marketed as Ampyra in the United States by Acorda Therapeutics and as Fampyra in Europe. In Canada, the medication has been approved for use by Health Canada since February 10, 2012.

Basic Info

Chemical Name	4-aminopyridine
Synonyms	AMpyra; Dalfampridine; 4-Pyridinamine; 4-pyridinylamine; mi-w-3; pyridin-4-yl-amine; 4APY; 4-Aminopyridine; Neurelan; 4-AP; avitrol; 4-amino-pyridine; vmi10-3; p-amino pyridine; Prc 1237; pyridin-4-amine; pyridine-4-amine; EL 970;
CAS No.	504-24-5
Molecular Formula	C5H6N2
Molecular Weight	94.11450
PSA	38.91000
LogP	1.24500

Properties

Appearance & Physical State	white to yellowish crystal
Density	1.26
Boiling Point	273ºC
Melting Point	157-161ºC
Flash Point	156ºC
Stability	Stable under normal temperatures and pressures.
Storage Condition	0-6ºC

Safety Info

RTECS	US1750000
Hazard Class	6.1
Safety Statements	S1-S28-S37/39-S45
HS Code	2933399090
Packing Group	II
WGK Germany	3
RIDADR	UN 2671
Risk Statements	R28; R36/37/38
Hazard Codes	T+
Caution Statement	P261; P264; P301 + P310; P305 + P351 + P338
Hazard Declaration	H300; H315; H319; H335
Signal Word	Danger
Symbol	GHS06

Synthesis Route

4-methylpyridine+4-bromopyridine,hydrochloride→3-Aminopyridine+4-aminopyridine
4-Nitropyridine N-oxide→4-aminopyridine
1-hydroxypyridin-4-imine→4-aminopyridine

Precursor

1-hydroxypyridin-4-imine
4-bromopyridine
4-Nitropyridine N-oxide
4-(tert-Butoxycarbonylamino)pyridine

Downstream Product

N-Cyano-N-4-pyridinylimidoformamide
3,5-dinitropyridin-4-amine
2-chloro-5-nitro-N-pyridin-4-ylbenzamide
3-(1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluorohexyl)pyridin-4-amine

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