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Home > All categories> Biochemicals and Pharmaceutical Chemicals> Pharmaceutical Impurities> 4-amino-N-[(2R,3S)-3-amino-2-hydroxy-4-phenylbutyl]-N-(2-methylpropyl)benzenesulfonamide
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4-amino-N-[(2R,3S)-3-amino-2-hydroxy-4-phenylbutyl]-N-(2-methylpropyl)benzenesulfonamide

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Origin: China

Cas No: 169280-56-2

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Quick Details

    CAS No.:
    169280-56-2
    Other Names:
    Darunavir intermediates
    MF:
    C20H29N3O3S
    Place of Origin:
    China
    Type:
    Pharmaceutical Intermediates
    Purity:
    98%MIN
    Brand Name:
    Royal pharm
    Model Number:
    Darunavir intermediates
    Application:
    Used
    Appearance:
    solid
    MW:
    391.53

    Packaging&Delivery

    Packaging Details
    Drum&plastic bags or Aluninium foiled bag&zip lock bag
    Port
    Any port in China
    Lead Time:
    Quantity(Kilograms)1 - 1>1
    Est. Time(days)3To be negotiated

  • Property

    CAS No.: 169280-56-2 Formula: C20H29N3O3S Molecular Weight: 391.52800

    Description

    A metabolite of Darunavir.

    Basic Info

    Chemical Name 4-amino-N-[(2R,3S)-3-amino-2-hydroxy-4-phenylbutyl]-N-(2-methylpropyl)benzenesulfonamide
    Synonyms

    CAS No. 169280-56-2
    Molecular Formula C20H29N3O3S
    Molecular Weight 391.52800
    PSA 118.03000
    LogP 4.20870

    Properties

    Density 1.226 g/cm3
    Boiling Point 609.105ºC at 760 mmHg
    Flash Point 322.175ºC
    Refractive Index 1.605

    Synthesis Route

    4-nitro-N-((2R(syn),3S)-3-(N-benzyloxycarbonylamino)-2-hydroxy-4-phenylbutyl)-N-isobutyl-benzenesulfonamide→4-amino-N-[(2R,3S)-3-amino-2-hydroxy-4-phenylbutyl]-N-(2-methylpropyl)benzenesulfonamide
    N-[3S-[(phenylmethoxycarbonyl)amino]-2R-hydroxy-4-phenylbutyl]-2-methylpropylamine+4-Nitrobenzenesulfonyl chloride→4-amino-N-[(2R,3S)-3-amino-2-hydroxy-4-phenylbutyl]-N-(2-methylpropyl)benzenesulfonamide
    tert-butyl N-[(2S,3R)-3-hydroxy-4-[2-methylpropyl-(4-nitrophenyl)sulfonylamino]-1-phenylbutan-2-yl]carbamate→4-amino-N-[(2R,3S)-3-amino-2-hydroxy-4-phenylbutyl]-N-(2-methylpropyl)benzenesulfonamide

    Precursor

    4-Nitrobenzenesulfonyl chloride
    tert-butyl N-[(2S,3R)-4-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl]carbamate
    N-[3S-[(phenylmethoxycarbonyl)amino]-2R-hydroxy-4-phenylbutyl]-2-methylpropylamine
    4-nitro-N-((2R(syn),3S)-3-(N-benzyloxycarbonylamino)-2-hydroxy-4-phenylbutyl)-N-isobutyl-benzenesulfonamide

    Downstream Product

    tert-butyl N-[(2S,3R)-4-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl]carbamate
    [14C]-Darunavir ethanolate

Hot tags: 4-amino-n-[(2r,3s)-3-amino-2-hydroxy-4-phenylbutyl]-n-(2-methylpropyl)benzenesulfonamide, China, manufacturers, suppliers, factory, wholesale, low price, high quality
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