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4-Amino-1-methyl-3-propyl-1H-pyrazole-5-carboxamide

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Origem: China

Cas No: 139756-02-8

Especificação: 99%Min

Quantidade de ordem min: 1 /kg

Capacidade de fornecimento: 100 mt/month

Tempo de espera: 7 dias para OEM, 3 dias para produtos prontos

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Descrição do produto

Quick Details
CAS No.:
139756-02-8
Other Names:
139756-02-8
MF:
C8H14N4O, C8H14N4O
EINECS No.:
1533716-785-6
Place of Origin:
Jiangsu, China
Type:
Pharmaceutical Intermediates
Purity:
N/A
Brand Name:
Monheit
Model Number:
139756-02-8
Application:
sildenafil
Appearance:
White powder, White powder
Product name:
Top Class 1H-Pyrazole-5-Carboxamide.4-Amino-1-Methyl-3-N-Propyl Price
MW:
182.22
Origin:
China
CAS:
139756-02-8
Sample:
available
Melting point:
98-101 °C(lit.)
Storage temp.:
Refrigerator
Packing:
As per customers' requirement
Packaging&Delivery
Packaging Details
Safe packaging will be used for Top Class 1H-Pyrazole-5-Carboxamide.4-Amino-1-Methyl-3-N-Propyl Price 139756-02-8
Packaging Details:As per customers' requirement.
Port
Shanghai, Qingdao

Property

CAS No.: 139756-02-8 Formula: C8H14N4O Molecular Weight: 182.22300

Description

An impurity in the synthesis of Sildenafil.

Basic Info

Chemical Name	4-Amino-1-methyl-3-propyl-1H-pyrazole-5-carboxamide
Synonyms	4-Amino-1-methyl-3-n-propyl-5-pyrazolecarboxamide; 4-Amino-1-methyl-3-N-propyl-1H-pyrazole-5-carboxamide; 1H-Pyrazole-5-carboxamide,4-amino-1-methyl-3-n-propyl; 4-amino-2-methyl-5-propylpyrazole-3-carboxamide;
CAS No.	139756-02-8
Molecular Formula	C8H14N4O
Molecular Weight	182.22300
PSA	86.93000
LogP	1.33520

Properties

Density	1.32g/cm3
Boiling Point	325.9ºC at 760mmHg
Melting Point	98-101ºC
Flash Point	150.9ºC
Refractive Index	1.618
Vapor Pressure	0.000223mmHg at 25°C

Safety Info

Safety Statements	S26-S36
HS Code	2933199090
WGK Germany	3
Risk Statements	R36/37/38
Hazard Codes	Xi
Hazard Declaration	H315; H319; H335
Signal Word	Warning
Caution Statement	P261; P305 + P351 + P338
Symbol	GHS07

Synthesis Route

2-methyl-4-nitro-5-propylpyrazole-3-carboxamide→4-Amino-1-methyl-3-propyl-1H-pyrazole-5-carboxamide
1-Methyl-3-propyl-1H-pyrazole-5-carboxylic acid→4-Amino-1-methyl-3-propyl-1H-pyrazole-5-carboxamide
2-methyl-4-nitro-5-propylpyrazole-3-carboxylic acid→4-Amino-1-methyl-3-propyl-1H-pyrazole-5-carboxamide

Precursor

2-methyl-4-nitro-5-propylpyrazole-3-carboxylic acid
2-methyl-4-nitro-5-propylpyrazole-3-carboxamide
1-Methyl-3-propyl-1H-pyrazole-5-carboxylic acid
ethyl 2-(2-(1-cyanobutyl)-1-methylhydrazinyl)acetate

Downstream Product

5-[2-ethoxy-5-[4-(2-hydroxyethyl)piperazin-1-yl]sulfonylphenyl]-1-methyl-3-propyl-4H-pyrazolo[4,3-d]pyrimidin-7-one
sildenafil
5-[2-ethoxy-5-(4-methylpiperazin-1-yl-sulphonyl)phenyl]-1-methyl-3-n-propyl-1-hydro-7-ethoxypyrazolo[4,3-d]pyrimidine
4-[(2-ethoxybenzoyl)amino]-2-methyl-5-propylpyrazole-3-carboxamide

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