Home > Organosilicon Compounds> 4-amino-1-[(2R,5S)-2-[[tert-butyl(dimethyl)silyl]oxymethyl]-1,3-oxathiolan-5-yl]-5-fluoropyrimidin-2-one

4-amino-1-[(2R,5S)-2-[[tert-butyl(dimethyl)silyl]oxymethyl]-1,3-oxathiolan-5-yl]-5-fluoropyrimidin-2-one

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Origin: China

Cas No: 1365246-84-9

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 1365246-84-9 Formula: C14H24FN3O3SSi Molecular Weight: 361.50800

Basic Info

Chemical Name	4-amino-1-[(2R,5S)-2-[[tert-butyl(dimethyl)silyl]oxymethyl]-1,3-oxathiolan-5-yl]-5-fluoropyrimidin-2-one
Synonyms	2-O-tert-Butyldimethylsilyl (-)-Emtricitabine; (-)-5'-O-(t-butyldimethylsilyl)-5-fluoro-2',3'-dideoxy-3'-thiacytidine; 4-AMINO-1-((2R,5S)-2-((TERT-BUTYLDIMETHYLSILYLOXY)METHYL)-1,3-OXATHIOLAN-5-YL)-5-FLUOROPYRIMIDIN-2(1H)-ONE;
CAS No.	1365246-84-9
Molecular Formula	C14H24FN3O3SSi
Molecular Weight	361.50800
PSA	105.66000
LogP	2.91690

Synthesis Route

tert-butyldimethylsilyl chloride+Emtricitabine→4-amino-1-[(2R,5S)-2-[[tert-butyl(dimethyl)silyl]oxymethyl]-1,3-oxathiolan-5-yl]-5-fluoropyrimidin-2-one

Precursor

tert-butyldimethylsilyl chloride
Emtricitabine

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