Início > Chiral Compounds> 4-amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidin-2-one

4-amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidin-2-one

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Origem: China

Cas No: 80791-93-1

Especificação: 99%Min

Quantidade de ordem min: 1 /kg

Capacidade de fornecimento: 80 mt/month

Tempo de espera: 7 dias para OEM, 3 dias para produtos prontos

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CAS No.: 80791-93-1 Formula: C9H11FIN3O4 Molecular Weight: 371.10400

Basic Info

Chemical Name	4-amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidin-2-one
Synonyms	5-iodo-2'-fluoroC; 2'-deoxy-2'-fluoro-5-iodocytidine; 5-iodo-2'-fluoro-2-deoxycytidine;
CAS No.	80791-93-1
Molecular Formula	C9H11FIN3O4
Molecular Weight	371.10400
PSA	110.60000
LogP	-0.40000

Synthesis Route

2'-Deoxy-2'-fluorocytidine→4-amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidin-2-one
3',5'-di-O-acetyl-2'-deoxy-2'-fluoro-5-iodocytosine hydrochloride→4-amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidin-2-one
ancitabine→4-amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidin-2-one

Precursor

ancitabine
2'-Deoxy-2'-fluorocytidine
3',5'-di-O-acetyl-2'-deoxy-2'-fluoro-5-iodocytosine hydrochloride

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