Home > Heterocyclic Compounds> 4-amino-1-[(2-methylpropan-2-yl)oxycarbonyl]piperidine-4-carboxylic acid

4-amino-1-[(2-methylpropan-2-yl)oxycarbonyl]piperidine-4-carboxylic acid

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Origin: China

Cas No: 183673-71-4

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Product Description

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CAS No.: 183673-71-4 Formula: C11H20N2O4 Molecular Weight: 244.28700

Description

An α,α-Disubstituted amino acid for preparation of water-soluble highly helical peptides.

Basic Info

Chemical Name	4-amino-1-[(2-methylpropan-2-yl)oxycarbonyl]piperidine-4-carboxylic acid
Synonyms	1-Boc-4-aminopiperidine-4-carboxylic Acid; 4-Amino-1-Boc-piperidine-4-carboxylic acid; 4-Amino-1-Boc-4-piperidinecarboxylic acid; 1-BOC-4-AMINO-4-PIPERIDINECARBOXYLIC ACID; h-pip(boc)-oh; 4-amino-1-(tert-butyloxycarbonyl)piperidine-4-carboxylic acid; 4-amino-1-(tert-butoxycarbonyl)-4-piperidinecarboxylic acid; 4-amino-1-boc-isonipecotic acid; 1-tert-butyl 4-amino-piperidine-1,4-dicarboxylate; 4,4-acp(1-n-boc); 4-tert-butoxycarbonyl-1,1-aminopiperidinylcarboxylic acid; 4-Amino-1-tert-butoxycarbonylpiperidine-4-carboxylic acid;
CAS No.	183673-71-4
Molecular Formula	C11H20N2O4
Molecular Weight	244.28700
PSA	92.86000
LogP	1.43760

Properties

Appearance & Physical State	white powder
Density	1.203g/cm3
Boiling Point	380.1ºC at 760mmHg
Melting Point	290ºC
Flash Point	183.7ºC
Refractive Index	1.513
Storage Condition	2-8ºC
Vapor Pressure	7.87E-07mmHg at 25°C

Safety Info

Safety Statements	S26-S37/39
HS Code	2933399090
Risk Statements	R36/37/38
Hazard Codes	Xi

Synthesis Route

tritert-butyl 2,4-dioxo-1,3,8-triazaspiro[4.5]decane-1,3,8-tricarboxylate→4-amino-1-[(2-methylpropan-2-yl)oxycarbonyl]piperidine-4-carboxylic acid
tert-butoxycarbonyl anhydride→4-amino-1-[(2-methylpropan-2-yl)oxycarbonyl]piperidine-4-carboxylic acid
1,3,8-Triazaspiro[4.5]decane-2,4-dione→4-amino-1-[(2-methylpropan-2-yl)oxycarbonyl]piperidine-4-carboxylic acid

Precursor

tert-butoxycarbonyl anhydride
4-Piperidone Hydrochloride Monohydrate
1,3,8-Triazaspiro[4.5]decane-2,4-dione
1-Boc-4-Piperidone

Downstream Product

4-Allyl-1-{[(2-methyl-2-propanyl)oxy]carbonyl}-4-piperidinecarbox ylic acid
4-(9H-fluoren-9-ylmethoxycarbonylamino)-1-[(2-methylpropan-2-yl)oxycarbonyl]piperidine-4-carboxylic acid
1-[(2-methylpropan-2-yl)oxycarbonyl]-4-[(2-methylpropan-2-yl)oxycarbonylamino]piperidine-4-carboxylic acid
1-[(2-methylpropan-2-yl)oxycarbonyl]-4-(phenylmethoxycarbonylamino)piperidine-4-carboxylic acid

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