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2,5-dichloropyrimidine

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Origin: China

Cas No: 22536-67-0

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Quick Details
CAS No.:
22536-67-0
Other Names:
2,5-Dichloropyrimidine
MF:
C4H2Cl2N2
EINECS No.:
22536-67-0
Place of Origin:
Shandong, China
Type:
Agrochemical Intermediates
Purity:
99%
Brand Name:
Finerchem
Model Number:
22536-67-0
Application:
Organic Intermediate
Appearance:
White powder
CAS:
22536-67-0
Product name:
2,5-Dichloropyrimidine
Appearence:
White powder
Molecular formula:
C4H2Cl2N2
Molecular Weight:
148.98
Packaging&Delivery
Packaging Details
Aluminum foil bag for within 10kg
Fiber drum for 10kg and more
Shipping: By air, by sea or by courier (VIP account of TNT, DHL, Fedex and EMS)
Port
Qingdao or Shanghai
Lead Time:
Quantity(Kilograms) 1 - 1 >1
Est. Time(days) 2 To be negotiated

Property

CAS No.: 22536-67-0 Formula: C4H2Cl2N2 Molecular Weight: 148.97800

Description

2,5-Dichloropyrimidine is a reactant that has been used in the synthesis of BI 207524, an Indole Diamide NS5B Thumb Pocket 1 Inhibitor for the potential treatment of chronic hepatitis C virus.

Basic Info

Chemical Name	2,5-dichloropyrimidine
Synonyms	2,5-Dichlor-pyrimidin; 2,5-chloropyrimidine; 2,5-Dichloropyrimidine; 2,5-dichloro-pyrimidine; dichloropyrimidine; Pyrimidine,2,5-dichloro;
CAS No.	22536-67-0
Molecular Formula	C4H2Cl2N2
Molecular Weight	148.97800
PSA	25.78000
LogP	1.78340

Properties

Density	1.493
Boiling Point	190ºC
Melting Point	57.0-57.5ºC
Flash Point	140ºC
Refractive Index	1.559
Vapor Pressure	0.0152mmHg at 25°C

Safety Info

HS Code	2933599090
Hazard Codes	C
Caution Statement	P273; P280; P305 + P351 + P338
Signal Word	Danger
Symbol	GHS05, GHS07, GHS09
Hazard Declaration	H302; H318; H400

Synthesis Route

2,4,5-Trichloropyrimidine→2,5-dichloropyrimidine
5-Chloro-2-hydroxy-pyrimidine→2,5-dichloropyrimidine
2-Amino-5-chloropyrimidine→2,5-dichloropyrimidine

Precursor

5-Chloro-2-hydroxy-pyrimidine
2-Amino-5-chloropyrimidine
2,4,5-Trichloropyrimidine
2-Hydroxypyrimidine hydrochloride

Downstream Product

5-Chloro-2-methylpyrimidine
1-(5-chloropyrimidin-2-yl)piperidin-4-ol
pyrimidine
5-Chloro-2-iodopyrimidine

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