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Picture of 2,4,5-Trichloropyrimidine

2,4,5-Trichloropyrimidine

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Origin: China

Cas No: 5750-76-5

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description
  • Quick Details

    CAS No.:
    5750-76-5
    Other Names:
    Ceritinib Intermediates
    MF:
    Ceritinib Intermediates
    EINECS No.:
    N/A
    Place of Origin:
    Hubei, China(Mainland)
    Type:
    Pharmaceutical Intermediates, Syntheses Material Intermediates
    Purity:
    99%min, 99% min
    Brand Name:
    hengheda
    Model Number:
    Ceritinib
    Application:
    Pharmaceutical Intermediates, Pharmaceutical Raw Intermediates
    Appearance:
    white powder, White powder
    Product name:
    Ceritinib Intermediates 2,4,5-Trichloropyrimidine cas 5750-76-5
    Function:
    pharm grade
    Grade:
    medicine grade
    COA:
    Available
    Stock:
    Available
    Assay test method:
    HPLC
    Shelf Life:
    2 Years

    Packaging&Delivery

    Packaging Details
    5 grams/Al-foil bag
    10 grams/Al-foil bag
    100 grams/Al-foil bag
    1kg/Al-foil bag
    or upon customers' request.
    Lead Time:
    Quantity(Grams)1 - 1>1
    Est. Time(days)15To be negotiated
  • Property

    CAS No.: 5750-76-5 Formula: C4HCl3N2 Molecular Weight: 183.42300

    Description

    2,4,5-Trichloropyrimidine is used in the synthesis of potent and selective anaplastic lymphoma kinase (ALK-5) inhibitors, used as an anti-tumor treatment. Also used in the synthesis of EGFR inhibitors.

    Basic Info

    Chemical Name 2,4,5-Trichloropyrimidine
    Synonyms

    2,5,6-TRICHLOROPYRIMIDINE;
    2,4,5-Trichlor-pyrimidin;
    2,4,5-trichloro-pyrimidine;
    trichloropyrimidine;
    5-chloro-2,4-dichloro-pyrimidine;
    2,3-DIHYDRO-1H-INDEN-5-YL HYDROSULFIDE;

    CAS No. 5750-76-5
    Molecular Formula C4HCl3N2
    Molecular Weight 183.42300
    PSA 25.78000
    LogP 2.43680

    Properties

    Appearance & Physical State Colorless to pale yellow liquid
    Density 1.6001
    Boiling Point 258.5ºC at 760 mmHg
    Flash Point >110ºC
    Refractive Index 1.574

    Safety Info

    Hazard Class 8
    Safety Statements S26-S36
    HS Code 2933599090
    WGK Germany 3
    Packing Group III
    RIDADR UN1760
    Risk Statements R36/37/38
    Hazard Codes Xi
    Symbol GHS07
    Caution Statement P261; P305 + P351 + P338
    Hazard Declaration H315; H319; H335
    Signal Word Warning

    Synthesis Route

    5-chlorouracil2,4,5-Trichloropyrimidine

    Precursor

    5-chlorouracil

    Downstream Product

    2,5-dichloropyrimidin-4-ol
    Pyrazolo[1,5-a]pyridine
    1-(2,5-dichloropyrimidin-4-yl)indole
    3-(2,5-dichloropyrimidin-4-yl)pyrazolo[1,5-a]pyridine

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