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2-Hydroxybenzonitrile

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Origin: China

Cas No: 611-20-1

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Quick Details
CAS No.:
611-20-1
Other Names:
2-hydroxy-benzonitril
MF:
C7H5NO
EINECS No.:
210-259-3
Place of Origin:
Shandong, China
Type:
Pharmaceutical Intermediates
Purity:
99.0%min, 99.0%min
Brand Name:
QDXIGEMA
Model Number:
N/A
Application:
Chemical Intermediate
Appearance:
White Powder
Product name:
2-Cyanophenol
CAS:
611-20-1
Molecular weight:
119.12
Boiling point:
149°C/1.9kPa
Color:
white
Name:
2-Cyanophenol
Melting point:
95-98℃
Synonyms:
2-Hydroxybenzonitrile
Usage:
The intermediates of bunylol
Packaging&Delivery
Packaging Details
25kg / drum
Port
QINGDAO PORT

Property

CAS No.: 611-20-1 Formula: C7H5NO Molecular Weight: 119.12100

Description

2-Hydroxybenzonitrile is used in the synthesis of CDK/GSK-3 inhibitors, for usage as therapeutics in Alzheimer’s.

Basic Info

Chemical Name	2-Hydroxybenzonitrile
Synonyms	2-Cyanophenol; Benzonitrile, 2-hydroxy-;
CAS No.	611-20-1
Molecular Formula	C7H5NO
Molecular Weight	119.12100
PSA	44.02000
LogP	1.26388

Properties

Appearance & Physical State	off-white to light brown powder
Density	1.1052 g/cm3 (99.6 C)
Boiling Point	149ºC (14 mmHg)
Melting Point	95-98ºC
Flash Point	149°C/14mm
Refractive Index	1.5372 (100ºC)
Water Solubility	soluble
Stability	Stable. Incompatible with strong oxidizing agents, strong bases.
Storage Condition	Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Safety Info

Hazard Class	6.1
Safety Statements	S26-S36
HS Code	29269095
WGK Germany	3
Packing Group	III
RIDADR	UN 3276
Risk Statements	R22; R36/37/38
Hazard Codes	Xn

Synthesis Route

Ethanol+benzo[d]isoxazol-3-yl(phenyl)methanone→2-Hydroxybenzonitrile+Ethyl benzoate
salicylaldehyde→2-Hydroxybenzonitrile+Salicylaldoxime
(E)-2-hydroxylbenzaldehyde oxime+phenyl isothiocyanate→2-Hydroxybenzonitrile+carbonyl sulfide

Precursor

2-Bromobenzonitrile
(E)-2-hydroxylbenzaldehyde oxime
2-chlorophenol
zinc,dicyanide

Downstream Product

2-[[(2-hydroxyphenyl)methylamino]methyl]phenol
5-BROMO-2-HYDROXYBENZONITRILE
3-BROMO-2-HYDROXYBENZONITRILE
3,5-DIBROMO-2-HYDROXYBENZONITRILE

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