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2-amino-2,2-diphenylacetic acid

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Origin: China

Cas No: 3060-50-2

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Product Description

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CAS No.: 3060-50-2 Formula: C14H13NO2 Molecular Weight: 227.25900

Description

2,2-Diphenylglycine is a decomposition product of Phenytoin, which reduces incidence of grand mal seizures; appears to stabilize excitable membranes perhaps through effects on Na+, K+, and Ca2+ channels.

Basic Info

Chemical Name	2-amino-2,2-diphenylacetic acid
Synonyms	2,2-DIMETHYL-5-HYDROXYMETHYL-1,3-DIOXANE; alpha,alpha-Diphenylglycine; GLYCINE,2,2-DIPHENYL; EINECS 221-299-6; 2,2-Diphenylglycine; 2,2-Diphenylglycine(Phenytoin RCA);
CAS No.	3060-50-2
Molecular Formula	C14H13NO2
Molecular Weight	227.25900
PSA	63.32000
LogP	2.67380

Properties

Appearance & Physical State	white powder
Density	1.231 g/cm3
Boiling Point	383.5ºC at 760 mmHg
Melting Point	244-247ºC
Flash Point	185.7ºC
Refractive Index	1.62

Safety Info

RTECS	MC0176000
Safety Statements	S24/25
HS Code	2922499990
WGK Germany	3

Synthesis Route

phenytoin→2-amino-2,2-diphenylacetic acid
benzilic acid→2-amino-2,2-diphenylacetic acid
P,P,P-triphenyl-N-(2,2,2-trichloro-1,2-diphenylethyl)phosphine imide→triphenylphosphane oxide+2-amino-2,2-diphenylacetic acid

Toxicity

Exposure Route	Type of Test	Species Observed	Dose/Duration	Toxic Effects
Intraperitoneal	TDLo - Lowest published toxic dose	Rodent - mouse	124 mg/kg,female 8 day(s) after conception	1.Reproductive-Fertility-post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)

Precursor

Benzhydrylamine
benzilic acid
Benzophenone oxime
P,P,P-triphenyl-N-(2,2,2-trichloro-1,2-diphenylethyl)phosphine imide

Downstream Product

3-benzyl-5,5-diphenylimidazolidine-2,4-dione
2-amino-2,2-diphenylethanol
1,1-Diphenyl-N-(3-pyridinylmethyl)methanimine
N-Benzhydrylcarbaminsaeuremethylester

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