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Home > Carbonyl Compounds> [2-(17-ethoxycarbonyloxy-11-hydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl] propanoate
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[2-(17-ethoxycarbonyloxy-11-hydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl] propanoate

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Origin: China

Cas No: 73771-04-7

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Quick Details

    CAS No.:
    73771-04-7
    Other Names:
    Prednitop
    MF:
    C27H36O8
    EINECS No.:
    277-590-3
    Place of Origin:
    Shandong, China
    Type:
    Antibiotic and Antimicrobial Agents
    Grade Standard:
    Medicine Grade
    Usage:
    Animal Pharmaceuticals
    Brand Name:
    FOUSI
    Model Number:
    FS73771-04-7
    Purity:
    99%MIN
    Product Name::
    Prednicarbate
    Molecular Weight::
    488.57
    Form:
    NEAT
    Appearance:
    White Powder
    Sample:
    Available
    Melting point::
    110-112°
    specific rotation::
    D20 +63°
    Solubility:
    insoluble in water
    Storage:
    Cool Dry Place
    Shelf life::
    2 Years

    Packaging&Delivery

    Packaging Details
    Packaging & Delivery
    Packaging Details
    Methyl Cellulose Package 25kg/bag or according to customer's requirement.
    Port
    Shanghai,Qingdao
    Port
    QINGDAO ,SHANGHAI
    Lead Time:
    Quantity(Grams)1 - 1>1
    Est. Time(days)7To be negotiated

  • Property

    CAS No.: 73771-04-7 Formula: C27H36O8 Molecular Weight: 488.57000

    Description

    Prednicarbate is a relatively new topical corticosteroid drug. It is similar in potency to hydrocortisone. Compared to other topical corticosteroids, like betamethasone, repeated prednicarbate use does not cause skin atrophy as quickly. Corticosteroids have always been an important part of the pharmacological arsenal of dermatology; however, their tendency to produce side-effects has caused the need to search for new preparations.
    It is nonhalogenated.

    Basic Info

    Chemical Name [2-(17-ethoxycarbonyloxy-11-hydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl] propanoate
    Synonyms

    Regemt;
    Prednicarbate;
    HOE-777;
    Prednisolone 17-(ethyl carbonate) 21-propionate;
    Dermatop;
    Regenit;
    Prednitop;
    S-77-0777;
    Prednicarbate (200 mg);

    CAS No. 73771-04-7
    Molecular Formula C27H36O8
    Molecular Weight 488.57000
    PSA 116.20000
    LogP 3.69930

    Properties

    Appearance & Physical State White cystalline powder
    Density 1.25 g/cm3
    Boiling Point 640.7ºC at 760 mmHg
    Melting Point 110 - 112ºC
    Flash Point 209.4ºC
    Refractive Index 1.56

    Synthesis Route

    ethyl [(8S,9S,10R,11S,13S,14S,17R)-11-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl] carbonate+Propionic anhydride→[2-(17-ethoxycarbonyloxy-11-hydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl] propanoate
    prednisolone→[2-(17-ethoxycarbonyloxy-11-hydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl] propanoate
    Prednisolon-17α,21-diethylortho..→[2-(17-ethoxycarbonyloxy-11-hydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl] propanoate

    Precursor

    Prednisolon-17α,21-diethylortho..
    Propionyl chloride
    ethyl [(8S,9S,10R,11S,13S,14S,17R)-11-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl] carbonate
    Propionic anhydride

    Downstream Product

    [2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] propanoate
    ethyl [(8S,9S,10R,11S,13S,14S,17R)-11-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl] carbonate

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