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(-)-Pseudoephedrine

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Origin: China

Cas No: 321-97-1

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

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CAS No.: 321-97-1 Formula: C10H15NO Molecular Weight: 165.23200

Description

D-(-)-Pseudoephedrine, is an enantiomer of (+)-Pseudoephedrine Hydrochloride, a non-selective adrenergic agonist, used as nasal decongestant. Controlled precursor.

Basic Info

Chemical Name	(-)-Pseudoephedrine
Synonyms	(1r,2r)-ephedrine; (-)-y-Ephedrine; l-Pseudoephedrine base; CPDD 0049; (-)-threo-Ephedrine; R,R(-)-PSEUDOEPHEDRINE; PSEUDOEPHEDRINE BASE; S,S(+)-Pseudoephedrine;
CAS No.	321-97-1
Molecular Formula	C10H15NO
Molecular Weight	165.23200
PSA	32.26000
LogP	1.71880

Properties

Appearance & Physical State	white to almost white crystalline powder
Density	1.015 g/cm3
Boiling Point	255ºC at 760 mmHg
Melting Point	118-120ºC
Flash Point	85.6ºC
Stability	Stable at room temperature in closed containers under normal storage and handling conditions.
Storage Condition	Refrigerator (+4ºC)

Safety Info

RTECS	UL5750500
Safety Statements	S26-S37/39
HS Code	2922199090
WGK Germany	3
Risk Statements	R20/21/22; R36/37/38
Hazard Codes	Xn

Synthesis Route

(2S)-2-amino-N-[(1R,2R)-1-hydroxy-1-phenylpropan-2-yl]-N-methylpent-4-enamide→(S)-(-)-2-Amino-4-Pentenoic Acid+(-)-Pseudoephedrine

Toxicity

Exposure Route	Type of Test	Species Observed	Dose/Duration	Toxic Effects
Intraperitoneal	LD50 - Lethal dose, 50 percent kill	Rodent - mouse	248 mg/kg	1.Behavioral-altered sleep time (including change in righting reflex) 2.Behavioral-tremor 3.Behavioral-convulsions or effect on seizure threshold
Intravenous	LD50 - Lethal dose, 50 percent kill	Rodent - mouse	105 mg/kg	1.Behavioral-altered sleep time (including change in righting reflex) 2.Behavioral-changes in motor activity (specific assay) 3.Lungs, Thorax, or Respiration-dyspnea

Downstream Product

(2S)-2-amino-N-[(1R,2R)-1-hydroxy-1-phenylpropan-2-yl]-N-methylpent-4-enamide
N-[(1R,2R)-1-hydroxy-1-phenylpropan-2-yl]-N-methylpropanamide
(-)-(1R,2R)-N-(3,4-dimethoxyphenethyl)pseudoephedrine
[2-[[(1R,2R)-1-hydroxy-1-phenylpropan-2-yl]-methylamino]-2-oxoethyl]azanium

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