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(-)-Pseudoephedrine

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Origin: China

CasNo: 321-97-1

specification: 99%min

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  • Products Specification
  • Description
  • Property

    CAS No.: 321-97-1 Formula: C10H15NO Molecular Weight: 165.23200

    Description

    D-(-)-Pseudoephedrine, is an enantiomer of (+)-Pseudoephedrine Hydrochloride, a non-selective adrenergic agonist, used as nasal decongestant. Controlled precursor.

    Basic Info

    Chemical Name (-)-Pseudoephedrine
    Synonyms

    (1r,2r)-ephedrine;
    (-)-y-Ephedrine;
    l-Pseudoephedrine base;
    CPDD 0049;
    (-)-threo-Ephedrine;
    R,R(-)-PSEUDOEPHEDRINE;
    PSEUDOEPHEDRINE BASE;
    S,S(+)-Pseudoephedrine;

    CAS No. 321-97-1
    Molecular Formula C10H15NO
    Molecular Weight 165.23200
    PSA 32.26000
    LogP 1.71880

    Properties

    Appearance & Physical State white to almost white crystalline powder
    Density 1.015 g/cm3
    Boiling Point 255ºC at 760 mmHg
    Melting Point 118-120ºC
    Flash Point 85.6ºC
    Stability Stable at room temperature in closed containers under normal storage and handling conditions.
    Storage Condition Refrigerator (+4ºC)

    Safety Info

    RTECS UL5750500
    Safety Statements S26-S37/39
    HS Code 2922199090
    WGK Germany 3
    Risk Statements R20/21/22; R36/37/38
    Hazard Codes Xn

    Synthesis Route

    (2S)-2-amino-N-[(1R,2R)-1-hydroxy-1-phenylpropan-2-yl]-N-methylpent-4-enamide(S)-(-)-2-Amino-4-Pentenoic Acid+(-)-Pseudoephedrine

    Toxicity

    Exposure Route Type of Test Species Observed Dose/Duration Toxic Effects
    Intraperitoneal LD50 - Lethal dose, 50 percent kill Rodent - mouse 248 mg/kg 1.Behavioral-altered sleep time (including change in righting reflex)
    2.Behavioral-tremor
    3.Behavioral-convulsions or effect on seizure threshold
    Intravenous LD50 - Lethal dose, 50 percent kill Rodent - mouse 105 mg/kg 1.Behavioral-altered sleep time (including change in righting reflex)
    2.Behavioral-changes in motor activity (specific assay)
    3.Lungs, Thorax, or Respiration-dyspnea

    Downstream Product

    (2S)-2-amino-N-[(1R,2R)-1-hydroxy-1-phenylpropan-2-yl]-N-methylpent-4-enamide
    N-[(1R,2R)-1-hydroxy-1-phenylpropan-2-yl]-N-methylpropanamide
    (-)-(1R,2R)-N-(3,4-dimethoxyphenethyl)pseudoephedrine
    [2-[[(1R,2R)-1-hydroxy-1-phenylpropan-2-yl]-methylamino]-2-oxoethyl]azanium

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