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sulfisoxazole

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Origin: China

Cas No: 127-69-5

Specification: 99%min

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 127-69-5 Formula: C11H13N3O3S Molecular Weight: 267.30400

    Description

    Sulfisoxazole is a sulfonamide based antibacterial that exhibits activity against wide spectrum of gram-negative and gram-positive bacterium.

    Basic Info

    Chemical Name sulfisoxazole
    Synonyms

    Benzenesulfonamide, 4-amino-N-(3,4-dimethyl-5-isoxazolyl)-;
    N1-(3,4-Dimethyl-5-isoxazolyl)sulfanilamide;
    4-amino-N-(3,4-dimethyl-1,2-oxazol-5-yl)benzenesulfonamide;
    4-Amino-N-(3,4-d;
    Sulfisoxazole;
    4-Amino-N-(3,4-dimethylisoxazol-5-yl)-benzenesulfonamide;
    Sulfafurazole;
    4-Amino-N-(3,4-dimethyl-5-isoxazolyl)benzenesulfonamide;
    4-Amino-N-(3,4-dimethylisoxazol-5-yl)benzenesulfonamide;

    CAS No. 127-69-5
    Molecular Formula C11H13N3O3S
    Molecular Weight 267.30400
    PSA 106.60000
    LogP 3.40940

    Properties

    Appearance & Physical State white to cream powder
    Density 1.411g/cm3
    Boiling Point 482.2ºC at 760mmHg
    Melting Point 195ºC
    Flash Point 245.4ºC
    Refractive Index 1.626
    Stability Stable. Incompatible with strong oxidizing agents.
    Storage Condition 2-8ºC
    Vapor Pressure 1.86E-09mmHg at 25°C

    Safety Info

    RTECS WO9100000
    Safety Statements S26-S36
    HS Code 2935009090
    WGK Germany 2
    Risk Statements R36/37/38
    Hazard Codes Xi

    Synthesis Route

    N-(3,4-dimethyl-1,2-oxazol-5-yl)-4-nitrobenzenesulfonamide→sulfisoxazole
    3,4-dimethyl-1,2-oxazol-5-amine→sulfisoxazole
    N-[4-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]phenyl]acetamide→sulfisoxazole

    Precursor

    4-Nitrobenzenesulfonyl chloride
    N-Acetylsulfanilyl chloride
    N-(3,4-dimethyl-1,2-oxazol-5-yl)-4-nitrobenzenesulfonamide
    3,4-dimethyl-1,2-oxazol-5-amine

    Downstream Product

    N-(4-aminophenyl)sulfonyl-N-(3,4-dimethyl-1,2-oxazol-5-yl)acetamide
    3,4-dimethyl-1,2-oxazol-5-amine
    3,4-Dimethyl-1,2-oxazol-5-ol
    N-[4-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]phenyl]acetamide

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