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sphinganine

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Origin: China

Cas No: 764-22-7

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 764-22-7 Formula: C18H39NO2 Molecular Weight: 301.50800

Description

Biosynthetic precursor of Sphingosine. Inhibits protein kinase C.

Basic Info

Chemical Name	sphinganine
Synonyms	erythro-Sphinganine; C18-Dihydrosphingosine; D-erythro-Sphinganine; Dihydrosphingosine; Dihydro-C18-sphingosine; (2S,3R)-2-aminooctadecane-1,3-diol; D-erythro-2-Amino-1,3-octadecanediol; Octadephinganine; D-erythro-C18-Dihydrosphingosine;
CAS No.	764-22-7
Molecular Formula	C18H39NO2
Molecular Weight	301.50800
PSA	66.48000
LogP	4.84850

Properties

Density	0.927g/cm3
Boiling Point	446.2ºC at 760 mmHg
Melting Point	70-72ºC
Flash Point	223.7ºC
Refractive Index	1.477
Storage Condition	-20ºC Freezer

Synthesis Route

sphingosine→sphinganine
(2S,3R,4E)-2-azido-1,3-dibenzyloxyoctadeca-4-ene→sphinganine
tert-butyl N-[(2S,3R)-1,3-dihydroxyoctadecan-2-yl]carbamate→sphinganine

Precursor

tert-butyl N-[(2S,3R)-1,3-dihydroxyoctadecan-2-yl]carbamate
(R)-N-((2S,3R)-1,3-dihydroxyoctadecan-2-yl)-2-methylpropane-2-sulfinamide
dibenzyl 1-((2S,3R,E)-1-(benzyloxy)-3-hydroxyoctadec-5-en-2-yl)hydrazine-1,2-dicarboxylate
sphingosine

Downstream Product

formic acid
hexadecanal
Ammonia
Palmitic acid

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