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spectinomycin

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Origin: China

Cas No: 1695-77-8

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 1695-77-8 Formula: C14H24N2O7 Molecular Weight: 332.35000

    Description

    Spectinomycin, sold under the tradename Trobicin among others, is an antibiotic useful for the treatment of gonorrhea infections. It is given by injection into a muscle.
    Common side effects include pain at the area of injection, rash, nausea, fever, and trouble sleeping. Severe allergic reactions may occasionally occur. It is generally safe to use during pregnancy. It may be used by those who are allergic to penicillin or cephalosporins. It is in the aminocyclitol class of drugs and works by stopping the making of protein by certain bacteria.
    Spectinomycin was discovered 1961. It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system. The wholesale cost in the developing world is about US$5 per dose. It is not available in the United States. It is made from the bacterium Streptomyces spectabilis.

    Basic Info

    Chemical Name spectinomycin
    Synonyms

    antibiotic2233wp;
    togamycin;
    spectinomicina;
    Spectinomycin;
    Spectacin;
    espectinomicina;
    spectam;
    trobicin;
    actinospectacin;

    CAS No. 1695-77-8
    Molecular Formula C14H24N2O7
    Molecular Weight 332.35000
    PSA 129.51000
    LogP -2.14380

    Properties

    Appearance & Physical State a white to pale buff crystalline dihydrochloride pentahydrate powder
    Density 1.43 g/cm3
    Boiling Point 583.1ºC at 760 mmHg
    Melting Point 185ºC
    Vapor Pressure 5.05E-16mmHg at 25°C

    Safety Info

    HS Code 3003209000

    Synthesis Route

    N,N-bis(benzyloxycarbonyl)-spectinomycin→spectinomycin
    4-O-acetyl-N,N'-<(benzyloxy)carbonyl>-4(R)-dihydrospectinomycin→spectinomycin
    dibenzyl ((1R,2S,3S,4R,5r,6S)-5-(((3aR,4S,6R,7aR)-2-methoxy-2,6-dimethyltetrahydro-4H-[1,3]dioxolo[4,5-c]pyran-4-yl)oxy)-2,4,6-tris(((2,2,2-trichloroethoxy)carbonyl)oxy)cyclohexane-1,3-diyl)bis(methylcarbamate)→spectinomycin

    Precursor

    dibenzyl ((1R,2S,3S,4R,5r,6S)-5-(((3aR,4S,6R,7aR)-2-methoxy-2,6-dimethyltetrahydro-4H-[1,3]dioxolo[4,5-c]pyran-4-yl)oxy)-2,4,6-tris(((2,2,2-trichloroethoxy)carbonyl)oxy)cyclohexane-1,3-diyl)bis(methylcarbamate)
    (2S,4R,6R)-2-(((1r,2R,3S,4S,5R,6S)-3,5-bis(((benzyloxy)carbonyl)(methyl)amino)-2,4,6-tris(((2,2,2-trichloroethoxy)carbonyl)oxy)cyclohexyl)oxy)-6-methyl-3-oxotetrahydro-2H-pyran-4-yl acetate
    N,N-bis(benzyloxycarbonyl)-spectinomycin
    4-O-acetyl-N,N'-<(benzyloxy)carbonyl>-4(R)-dihydrospectinomycin

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