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selegiline hydrochloride

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Origin: China

Cas No: 14611-52-0

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

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  • Products Specification
  • Product Description
  • Property

    CAS No.: 14611-52-0 Formula: C13H18ClN Molecular Weight: 223.74200

    Description

    Selegiline, also known as L-deprenyl is a substituted phenethylamine that at normal clinical doses it is a selective irreversible MAO-B inhibitor. In larger doses it loses its specificity and also inhibits MAO-A. It is available in pill form under many brand names and is used to reduce symptoms in early-stage Parkinson's disease. A transdermal patch (brand name, Emsam) is used to treat depression.

    Basic Info

    Chemical Name selegiline hydrochloride
    Synonyms

    (R)-N-Methyl-N-(1-phenylpropan-2-yl)prop-2-yn-1-amine hydrochloride;
    Selegiline HCl;
    (2R)-N-methyl-1-phenyl-N-prop-2-ynylpropan-2-amine,hydrochloride;
    R-(−)-Deprenyl hydrochloride;

    CAS No. 14611-52-0
    Molecular Formula C13H18ClN
    Molecular Weight 223.74200
    PSA 3.24000
    LogP 2.98460

    Properties

    Appearance & Physical State white Crystalline Solid
    Density 0.954g/cm3
    Boiling Point 272.5ºC at 760mmHg
    Melting Point 141-142ºC
    Flash Point 108.4ºC

    Safety Info

    RTECS DA0292500
    Hazard Class 6.1(b)
    Safety Statements S22-S26
    HS Code 2921519090
    WGK Germany 3
    Packing Group III
    RIDADR UN 3249

    Toxicity

    Exposure Route Type of Test Species Observed Dose/Duration Toxic Effects
    Subcutaneous LD50 - Lethal dose, 50 percent kill Rodent - rat 280 mg/kg 1.Details of toxic effects not reported other than lethal dose value
    Intravenous LD50 - Lethal dose, 50 percent kill Rodent - rat 81 mg/kg 1.Details of toxic effects not reported other than lethal dose value
    Unreported LD50 - Lethal dose, 50 percent kill Rodent - mouse 121 mg/kg 1.Details of toxic effects not reported other than lethal dose value

    Downstream Product

    R-(-)-Methamphetamine Hydrochloride
    1-[4-[2-[(4-chlorophenyl)-phenylmethoxy]ethyl]piperazin-1-yl]propan-2-ol,oxalic acid

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