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S-Trityl-L-cysteine

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Origin: China

Cas No: 2799-07-7

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 2799-07-7 Formula: C22H21NO2S Molecular Weight: 363.47300

Description

A protected cysteine for peptide synthesis. S-Trityl-L-cysteine (STLC) is a tight-binding inhibitor of Eg5 that prevents mitotic progression. It has proven antitumor activity as shown in the NCI 60 tumor cell line screen.

Basic Info

Chemical Name	S-Trityl-L-cysteine
Synonyms	EG5 INHIBITOR II; Cys(Trt)-OH; H-CYS(TRT)-OH; L-Cys(trt)-OH; S-Tritylcysteine; (R)-S-Tritylcysteine; S-Trt-L-Lys-OH; TRITYL-L-CYSTEINE; H-L-Cys(Trt)-OH; CYSTEINE(TRT)-OH; Tritylthioalanine;
CAS No.	2799-07-7
Molecular Formula	C22H21NO2S
Molecular Weight	363.47300
PSA	88.62000
LogP	4.82390

Properties

Appearance & Physical State	almost white to light yellow granular powder
Density	1.232 g/cm3
Boiling Point	524.7ºC at 760 mmHg
Melting Point	182-183ºC
Flash Point	271.2ºC
Refractive Index	111 ° (C=0.8, 0.04mol Ethanolic HCl)
Storage Condition	-20ºC
Vapor Pressure	7.71E-12mmHg at 25°C

Safety Info

RTECS	AY7710000
Safety Statements	S22-S24/25
HS Code	2930909090
WGK Germany	3
Risk Statements	R22
Hazard Codes	Xn

Synthesis Route

Triphenylmethanol+L-Cysteine hydrochloride→S-Trityl-L-cysteine
L-Cysteine hydrochloride+Triphenylmethyl Chloride→S-Trityl-L-cysteine
Triphenylmethanol+L-Cysteine→S-Trityl-L-cysteine

Precursor

Triphenylmethyl Chloride
Triphenylmethanol
L-Cysteine hydrochloride
FMOC-S-trityl-L-cysteine

Downstream Product

triphenylmethane
L-Cystine
N-Carbobenzoxy-S-trityl-L-cystein
(2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-tritylsulfanylpropanoic acid

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