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Home > Chiral Compounds> (S)-(-)-2-Hydroxy-1,2,2-Triphenylethyl Acetate
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(S)-(-)-2-Hydroxy-1,2,2-Triphenylethyl Acetate

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Origin: China

Cas No: 95061-51-1

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 95061-51-1 Formula: C22H20O3 Molecular Weight: 332.39200

    Description

    (S)-2-Hydroxy-1,2,2-triphenylethyl Acetate is a reactant in the synthesis of Lankacidin derivatives as a 17-membered macrocyclic antibiotic.

    Basic Info

    Chemical Name (S)-(-)-2-Hydroxy-1,2,2-Triphenylethyl Acetate
    Synonyms

    [(1S)-2-hydroxy-1,2,2-triphenylethyl] acetate;

    CAS No. 95061-51-1
    Molecular Formula C22H20O3
    Molecular Weight 332.39200
    PSA 46.53000
    LogP 4.22690

    Properties

    Appearance & Physical State white to light yellow crystal powder
    Density 1.18g/cm3
    Boiling Point 487.6ºC at 760mmHg
    Melting Point 246-249ºC
    Flash Point 197.6ºC
    Refractive Index 1.603

    Safety Info

    Safety Statements S24/25
    HS Code 2915390090

    Synthesis Route

    (S)-(-)-1,1,2-Triphenylethane-1,2-diol+acetyl chloride→(S)-(-)-2-Hydroxy-1,2,2-Triphenylethyl Acetate
    bromobenzene+L-(+)-Mandelic Acid Ethyl Ester→(S)-(-)-2-Hydroxy-1,2,2-Triphenylethyl Acetate
    (S)-(+)-Methyl mandelate→(S)-(-)-2-Hydroxy-1,2,2-Triphenylethyl Acetate

    Precursor

    (S)-(-)-1,1,2-Triphenylethane-1,2-diol
    acetyl chloride
    L-(+)-Mandelic Acid Ethyl Ester
    (S)-(+)-Methyl mandelate

    Downstream Product

    (S)-(-)-1,1,2-Triphenylethane-1,2-diol
    (3S,4S)-3-hydroxy-6-methyl-4-[(2-methylpropan-2-yl)oxycarbonylamino]heptanoic acid
    (3R,4S)-3-hydroxy-6-methyl-4-[(2-methylpropan-2-yl)oxycarbonylamino]heptanoic acid
    tert-Butyl (E)-7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-5-hydroxy-3-oxo-6-heptenoate

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