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(R)-1-(3,5-Bis-Trifluoromethyl-Phenyl)-Ethanol

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Origin: China

Cas No: 127852-28-2

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Quick Details
CAS No.:
127852-28-2
Other Names:
R-MBT-PEL
MF:
C10H8F6O
EINECS No.:
603-245-7
Place of Origin:
China
Type:
Pharmaceutical Intermediates
Purity:
99.0-101.0%
Brand Name:
Natural Micron Pharm Tech
Model Number:
127852-28-2
Application:
Pharmaceutical Intermediates
Appearance:
White powder, White powder
Product name:
(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol
CAS:
127852-28-2
Molecular Weight:
258.16
Grade:
Phamaceutical Grade/Cosmetic Grade
Synonyms:
127852-28-2
Assay:
99.0~101.0%
Shelf life:
Two Years
Storage:
Cool Dry Place
Molecular formula:
C10H8F6O
Packaging&Delivery
Packaging Details
1kg/Aluminum Foil Bag
25kg/Drum
25kg/Carton
Port
Shanghai/Shenzhen/Qingdao
Lead Time:
Quantity(Kilograms) 1 - 500 >500
Est. Time(days) 3 To be negotiated

Property

CAS No.: 127852-28-2 Formula: C10H8F6O Molecular Weight: 258.16000

Description

(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol is an intermediate in the synthesis of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1. Antiemetic.

Basic Info

Chemical Name	(R)-1-(3,5-Bis-Trifluoromethyl-Phenyl)-Ethanol
Synonyms	(R)-3,5-Bis(trifluoromethyl)-α-methylbenzyl Alcohol; (1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethanol; R-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol; (R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethan-1-ol; (R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol; (R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethyl Alcohol;
CAS No.	127852-28-2
Molecular Formula	C10H8F6O
Molecular Weight	258.16000
PSA	20.23000
LogP	3.77750