Home > Organosilicon Compounds> methyl (5R)-5-[(1R,3aS,4E,7aR)-4-[(2Z)-2-[(3R,5R)-3,5-bis[[tert-butyl(dimethyl)silyl]oxy]-2-methylidenecyclohexylidene]ethylidene]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-1-yl]hexanoate

methyl (5R)-5-[(1R,3aS,4E,7aR)-4-[(2Z)-2-[(3R,5R)-3,5-bis[[tert-butyl(dimethyl)silyl]oxy]-2-methylidenecyclohexylidene]ethylidene]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-1-yl]hexanoate

Get Latest Price >

FOB Price contact us for price

Origin: China

Cas No: 145372-43-6

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

Vendor:

Payment Terms:

Inquiry now

* Send an Inquiry to us

Add to wishlist

* Name your price
* Start order doesn't mean buying now

Products Specification
Product Description

Property

CAS No.: 145372-43-6 Formula: C38H68O4Si2 Molecular Weight: 645.11500

Description

A novel 1,25-Dihydroxyvitamin D3 analog tested for vitamin D receptor binding affinity.

Basic Info

Chemical Name	methyl (5R)-5-[(1R,3aS,4E,7aR)-4-[(2Z)-2-[(3R,5R)-3,5-bis[[tert-butyl(dimethyl)silyl]oxy]-2-methylidenecyclohexylidene]ethylidene]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-1-yl]hexanoate
Synonyms
CAS No.	145372-43-6
Molecular Formula	C38H68O4Si2
Molecular Weight	645.11500
PSA	44.76000
LogP	11.16580

Synthesis Route

(8E)-8-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methylene-de-A,B-24(methoxycarbonyl)-cholestane+(3S,5R)-3,5-bis((tert-butyldimethylsilyl)oxy)oct-1-en-7-yn-2-yl trifluoromethanesulfonate→methyl (5R)-5-[(1R,3aS,4E,7aR)-4-[(2Z)-2-[(3R,5R)-3,5-bis[[tert-butyl(dimethyl)silyl]oxy]-2-methylidenecyclohexylidene]ethylidene]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-1-yl]hexanoate
Inhoffen-Lythgoe diol→methyl (5R)-5-[(1R,3aS,4E,7aR)-4-[(2Z)-2-[(3R,5R)-3,5-bis[[tert-butyl(dimethyl)silyl]oxy]-2-methylidenecyclohexylidene]ethylidene]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-1-yl]hexanoate
(1R,3aR,4S,7aR)-Octahydro-1-[(1S)-2-iodo-1-methylethyl]-7a-methyl-1H-inden-4-ol→methyl (5R)-5-[(1R,3aS,4E,7aR)-4-[(2Z)-2-[(3R,5R)-3,5-bis[[tert-butyl(dimethyl)silyl]oxy]-2-methylidenecyclohexylidene]ethylidene]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-1-yl]hexanoate

Precursor

Inhoffen-Lythgoe diol
(1R,1’S)-Octahydro-1-(2’-iodo-1’-methylethyl)-7a-methyl-inden-4-one
(3S,5R)-3,5-bis((tert-butyldimethylsilyl)oxy)oct-1-en-7-yn-2-yl trifluoromethanesulfonate
(1R,3aR,4S,7aR)-Octahydro-1-[(1S)-2-iodo-1-methylethyl]-7a-methyl-1H-inden-4-ol

Downstream Product

calcitriol

Hot tags: methyl (5r)-5-[(1r,3as,4e,7ar)-4-[(2z)-2-[(3r,5r)-3,5-bis[[tert-butyl(dimethyl)silyl]oxy]-2-methylidenecyclohexylidene]ethylidene]-7a-methyl-2,3,3a,5,6,7-hexahydro-1h-inden-1-yl]hexanoate, China, manufacturers, suppliers, factory, wholesale, low price, high quality