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methyl (2S)-5-(diaminomethylideneamino)-2-[(4-methylphenyl)sulfonylamino]pentanoate,hydrochloride

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Origin: China

Cas No: 1784-03-8

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Quick Details
CAS No.:
1784-03-8
MF:
1784-03-8
EINECS No.:
1784-03-8
Type:
Pharmaceutical Intermediates
Purity:
0.99
Application:
Pharmaceutical intermediates
Appearance:
powder
Product Name:
CAS No. 1784-03-8
Type of product:
pharmaceutical raw material
Grade:
Medical Grade
Packaging&Delivery
Selling Units:
Single item
Single package size:
15X10X10 cm
Single gross weight:
1.000 kg
Package Type:
```
According to the customer demand
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Lead Time:
Quantity(Kilograms) 1 - 10 >10
Est. Time(days) 5 To be negotiated

Property

CAS No.: 1784-03-8 Formula: C14H23ClN4O4S Molecular Weight: 378.87500

Description

N-4-Tosyl-L-arginine Methyl Ester Hydrochloride acts as a synthetic substrate of serine proteases and thus is used to determine serine proteases from diverse organic sources.

Basic Info

Chemical Name	methyl (2S)-5-(diaminomethylideneamino)-2-[(4-methylphenyl)sulfonylamino]pentanoate,hydrochloride
Synonyms	Nalpha-4-Tosyl-L-arginine methyl ester hydrochloride; (S)-Methyl 5-guanidino-2-(4-methylphenylsulfonamido)pentanoate hydrochloride; Nα-p-Toluenesulfonyl-L-arginine Methyl Ester Hydrochloride; N-4-Tosyl-L-arginine methyl ester hydrochloride; Nalpha-p-Toluenesulfonyl-L-arginine Methyl Ester Hydrochloride; Tos-Arg-OMe.HCl; Tos-Arg-Ome·Hcl; TAME hydrochloride; Nα-p-Tosyl-L-arginine methyl ester hydrochloride; Nalpha-Tosyl-L-arginine Methyl Ester Hydrochloride; TOS-ARG-OME HCL; Nα-Tosyl-L-arginine Methyl Ester Hydrochloride;
CAS No.	1784-03-8
Molecular Formula	C14H23ClN4O4S
Molecular Weight	378.87500
PSA	142.75000
LogP	3.54280

Properties

Appearance & Physical State	white fine crystalline powder
Boiling Point	544.1ºC at 760mmHg
Melting Point	145-147(lit.)ºC
Flash Point	282.9ºC
Refractive Index	-14 ° (C=4, H2O)
Storage Condition	-20ºC
Vapor Pressure	6.73E-12mmHg at 25°C

Safety Info

Safety Statements	S22; S24/25; S37/39; S26
HS Code	2935009090
WGK Germany	3
Risk Statements	R36/37/38
Hazard Codes	Xi

Synthesis Route

L-arginine→methyl (2S)-5-(diaminomethylideneamino)-2-[(4-methylphenyl)sulfonylamino]pentanoate,hydrochloride
p-Toluenesulfonyl chloride→methyl (2S)-5-(diaminomethylideneamino)-2-[(4-methylphenyl)sulfonylamino]pentanoate,hydrochloride
Methanol+Tos-Arg-OH→methyl (2S)-5-(diaminomethylideneamino)-2-[(4-methylphenyl)sulfonylamino]pentanoate,hydrochloride

Precursor

Tos-Arg-OH
p-Toluenesulfonyl chloride
L-arginine
Methanol

Downstream Product

Tos-Arg-NH2 HCl
Tos-Arg-OH

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