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Home > Organosilicon Compounds> methyl (2S)-3-[4-[tert-butyl(dimethyl)silyl]oxyphenyl]-2-[methyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]propanoate
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methyl (2S)-3-[4-[tert-butyl(dimethyl)silyl]oxyphenyl]-2-[methyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]propanoate

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Origin: China

Cas No: 112196-58-4

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 112196-58-4 Formula: C22H37NO5Si Molecular Weight: 423.61800

    Basic Info

    Chemical Name methyl (2S)-3-[4-[tert-butyl(dimethyl)silyl]oxyphenyl]-2-[methyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]propanoate
    Synonyms

    O-tert-Butyldimethylsilyl-N-methyl-N-t-butoxycarbonyl-L-tyrosine,Methyl Ester;
    Boc-(S)-N-MeTyr(TBS)-OMe;
    N-[(1,1-dimethylethoxy)carbonyl]-O-[(1,1-dimethylethyl)dimethylsilyl]-N-methyl-L-tyrosine Methyl Ester;

    CAS No. 112196-58-4
    Molecular Formula C22H37NO5Si
    Molecular Weight 423.61800
    PSA 65.07000
    LogP 5.02160

    Properties

    Density 1.03g/cm3
    Boiling Point 459.7ºC at 760 mmHg
    Flash Point 231.8ºC
    Refractive Index 1.488
    Vapor Pressure 1.23E-08mmHg at 25°C

    Synthesis Route

    methyl (2S)-3-[4-[tert-butyl(dimethyl)silyl]oxyphenyl]-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoate+iodomethane→methyl (2S)-3-[4-[tert-butyl(dimethyl)silyl]oxyphenyl]-2-[methyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]propanoate
    iodomethane+Boc-(S)-N-Me-Tyr(TBS)-OH→methyl (2S)-3-[4-[tert-butyl(dimethyl)silyl]oxyphenyl]-2-[methyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]propanoate
    methyl L-tyrosinate→methyl (2S)-3-[4-[tert-butyl(dimethyl)silyl]oxyphenyl]-2-[methyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]propanoate

    Precursor

    iodomethane
    methyl (2S)-3-[4-[tert-butyl(dimethyl)silyl]oxyphenyl]-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoate
    methyl (2S)-3-(4-hydroxyphenyl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoate
    methyl L-tyrosinate

    Downstream Product

    (2S)-3-(4-hydroxyphenyl)-2-[methyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]propanoic acid

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