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methoxychlor

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Origin: China

Cas No: 72-43-5

Specification: 99%min

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Supply Ability: 50 mt/month

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 72-43-5 Formula: C16H15Cl3O2 Molecular Weight: 345.64800

    Description

    Methoxy-DDT is a metabolite of 4,4'-Dichlorodiphenyltrichloroethane, a synthetic organochlorine insecticide that functions by opening sodium ion channels in the insects’ neurons, causing them to fire spontaneously which in turn leads to death.

    Basic Info

    Chemical Name methoxychlor
    Synonyms

    1-methoxy-4-[2,2,2-trichloro-1-(4-methoxyphenyl)ethyl]benzene;
    Marlate;
    [3H]-Methoxychlor;
    Metox;
    [14C]-Methoxychlor;
    Methoxy-DDT;
    1,1-di-(p-methoxyphenyl)-2,2,2-trichloroethane;
    1,1’-(2,2,2-trichloroethane-1,1-diyl)bis(4-methoxybenzene);
    Methoxcide;
    1,1,1-trichloro-2,2-bis(4-methoxyphenyl)ethane;
    1,1’-(2,2,2-trichloroethylidene)bis[4-methoxybenzene];
    Benzene, 1,1‘-(2,2,2-trichloroethylidene)bis[4-methoxy-;
    2,2-bis(p-methoxy phenyl)-1,1,1-trichloroethane;
    Dimethoxy-DDT;
    DMDT;
    p,p'-Methoxychlor;
    1,1,1-trichloro-2,2-bis(p-methoxyphenyl)-ethane;
    Maralate;

    CAS No. 72-43-5
    Molecular Formula C16H15Cl3O2
    Molecular Weight 345.64800
    PSA 18.46000
    LogP 5.20590

    Properties

    Appearance & Physical State COLOURLESS TO LIGHT YELLOW CRYSTALS , WITH CHARACTERISTIC ODOUR.
    Density 1.4 g/cm3
    Boiling Point greater than or equal to 100ºC.
    Melting Point 86-88ºC(lit.)
    Flash Point less than 60 degreesºC
    Refractive Index 1.57
    Stability Stable, but light sensitive. Combustible at high temperature. Corrodes aluminium and iron slowly.
    Storage Condition APPROX 4ºC

    Safety Info

    RTECS KJ3675000
    Safety Statements S7; S23; S36/37/39; S45
    HS Code 2909309011
    WGK Germany 3
    RIDADR UN 2811 6.1/PG 3
    Risk Statements R20/21/22
    Hazard Codes Xn; T; F; N

    Synthesis Route

    trichloroacetaldehyde+anisole→2,2,2-Trichloro-1-(4-methoxyphenyl)ethanol+methoxychlor
    trichloroacetaldehyde+anisole→methoxychlor
    Anisic aldehyde→methoxychlor

    GC Analysis

    Column type Active phase Temperature (°C) Retention Index (I) Temperature Control Method
    Capillary OV-1 220. 2413. isothermal
    Packed OV-1 200. 2401. isothermal
    Packed OV-1 210. 2418. isothermal
    Packed SE-30 - 2410. custom temperature program
    Capillary OV-1 - 2439.3 temperature ramp

    Toxicity

    Exposure Route Type of Test Species Observed Dose/Duration Toxic Effects
    Oral TDLo - Lowest published toxic dose Rodent - rat 266 mg/kg/19W-I 1.Liver-other changes
    2.Blood-other changes
    3.Biochemical-Enzyme inhibition, induction, or change in blood or tissue levels-dehydrogenases
    Oral TDLo - Lowest published toxic dose Rodent - rat 602 mg/kg/43W-I 1.Biochemical-Enzyme inhibition, induction, or change in blood or tissue levels-dehydrogenases
    2.Biochemical-Enzyme inhibition, induction, or change in blood or tissue levels-other oxidoreductases
    3.Biochemical-Enzyme inhibition, induction, or change in blood or tissue levels-transaminases
    Oral TDLo - Lowest published toxic dose Rodent - rat 18200 mg/kg/2Y-C 1.Tumorigenic-Carcinogenic by RTECS criteria
    2.Reproductive-Tumorigenic effects-prostate tumors

    Precursor

    anisole
    Anisic aldehyde
    2,2,2-Trichloro-1-(4-methoxyphenyl)ethanol
    trichloroacetaldehyde

    Downstream Product

    4,4'-Dimethoxybenzophenone
    1-methoxy-4-[(E)-2-(4-methoxyphenyl)ethenyl]benzene
    1-[2,2-dichloro-1-(4-methoxyphenyl)ethyl]-4-methoxybenzene
    1,1,4,4-tetrakis(4-methoxyphenyl)-2,2,3,3-tetrachlorobutane

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