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mesoridazine

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Origin: China

Cas No: 5588-33-0

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

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  • Products Specification
  • Product Description
  • Property

    CAS No.: 5588-33-0 Formula: C21H26N2OS2 Molecular Weight: 386.57400

    Description

    Mesoridazine (Serentil) is a piperidine neuroleptic drug belonging to the class of drugs called phenothiazines, used in the treatment of schizophrenia. It is a metabolite of thioridazine. The drug's name is derived from the methylsulfoxy and piperidine functional groups in its chemical structure.
    It has central antiadrenergic, antidopaminergic, antiserotonergic and weak muscarinic anticholinergic effects.
    Serious side effects include akathisia, tardive dyskinesia and the potentially fatal neuroleptic malignant syndrome.
    Mesoridazine was withdrawn from the United States market in 2004 due to dangerous side effects, namely irregular heart beat and QT-prolongation of the electrocardiogram.
    It currently appears to be unavailable worldwide.

    Basic Info

    Chemical Name mesoridazine
    Synonyms

    10-[2-(1-methyl-2-piperidyl)ethyl]-2-methylsulphinylphenothiazine;
    10-[2-(1-methylpiperidin-2-yl)ethyl]-2-methylsulfinylphenothiazine;
    Lidanil;
    Mesoridazinum;
    10-[2-(1-methylpiperidin-2-yl)ethyl]-2-(methylsulfinyl)-10H-phenothiazine;
    Mesoridazine;
    Thioridazine-2-sulfoxide;
    10-{2-[(RS)1-methylpiperidin-2-yl]ethyl}-2-methylsulfinyl-10H-phenothiazine;
    Thioridazine thiomethyl sulfoxide;
    Mesoridazina;
    Tps23;
    Calodal;
    Serentil;
    Lidanar;

    CAS No. 5588-33-0
    Molecular Formula C21H26N2OS2
    Molecular Weight 386.57400
    PSA 68.06000
    LogP 5.76970

    Properties

    Density 1.3g/cm3
    Boiling Point 570.5ºC at 760mmHg
    Flash Point 298.9ºC
    Refractive Index 1.694

    Synthesis Route

    thioridazinemesoridazine

    Precursor

    thioridazine

    Downstream Product

    Thioridazine 2-Sulfone

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