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menaquinone-7

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Origin: China

Cas No: 2124-57-4

Specification: 99%min

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 2124-57-4 Formula: C46H64O2 Molecular Weight: 648.99900

    Description

    Menaquinones are isoprenoid quinones of the naphthalene series and belongs to the K2 Vitamin homologs. Menaquinones were originally discovered as the anti-hemorrhagic factor and now encompasses a variety of physiological processes. Menaquinone 7 belongs to the class of K2-Vitamins homologs. Menaquinone 7 has been identified as the most bioactive cofactor for the carboxylation reaction of Gla-proteins such as osteocalcin and matrix-Gla protein, which plays a crucial role in building and maintaining overall bone health.

    Basic Info

    Chemical Name menaquinone-7
    Synonyms

    Menaquinone 7;
    Vitamin K2 MK-7;
    2-((2E,6E,10E,14E,18E,22E)-3,7,11,15,19,23,27-heptamethyloctacosa-2,6,10,14,18,22,26-heptaen-1-yl)-3-methylnaphthalene-1,4-dione;
    (all-E)-2-(3,7,11,15,19,23,27-heptamethyl-2,6,10,14,18,22,26-octacosaheptaenyl)-3-methyl-1,4-naphthalenedione;
    Vitamin K2(35);
    2-[(2E,6E,10E,14E,18E,22E)-3,7,11,15,19,23,27-heptamethyloctacosa-2,6,10,14,18,22,26-heptaenyl]-3-methylnaphthalene-1,4-dione;
    Vitamin MK 7;
    Menaquinone K7;
    2-methyl-3-all-trans-farnesyl digeranyl-1,4-naphthoquinone;
    1,4-Naphthalenedione,2-(3,7,11,15,19,23,27-heptamethyl-2,6,10,14,18,22,26-octacosaheptaenyl)-3-methyl-,(all-E);
    MK-7;

    CAS No. 2124-57-4
    Molecular Formula C46H64O2
    Molecular Weight 648.99900
    PSA 34.14000
    LogP 14.09740

    Properties

    Density 0.961
    Boiling Point 200ºC at 0.0002 MM HG (SOME DECOMP)
    Melting Point 54ºC
    Flash Point 254.9ºC
    Refractive Index 1.532
    Vapor Pressure 1.38E-20mmHg at 25°C

    Safety Info

    Caution Statement P210; P261; P280; P305 + P351 + P338; P370 + P378; P403 + P235
    Symbol GHS02, GHS07
    Signal Word Danger
    Hazard Declaration H225; H302 + H312 + H332; H319

    Synthesis Route

    (2-trans,6-trans)-farnesol→menaquinone-7
    (2E,6E)-farnesyl acetate→menaquinone-7
    E,E,E-12-hydroxyfarnesyl acetate→menaquinone-7

    Precursor

    (E,E)-3,7,11-trimethyl-2,6,10-dodecatrienyl bromide
    (2E,6E,10E)-12-bromo-3,7,11-trimethyl-2,6,10-dodecatrienyl acetate
    (2-trans,6-trans)-farnesol
    (2E,6E)-farnesyl acetate

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