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menadiol

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Origin: China

Cas No: 481-85-6

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  • Products Specification
  • Product Description
  • Property

    CAS No.: 481-85-6 Formula: C11H10O2 Molecular Weight: 174.19600

    Description

    Menadiol is an organic compound with the formula C6H4(COH)2(CH)(CH3). It is formally a derivative of p-hydroquinone. It is an intermediate in the synthesis of vitamin K4. It is oxidized to menadione.

    Basic Info

    Chemical Name menadiol
    Synonyms

    Methylnaphthohydroquinone;
    2-methylnaphthalene-1,4-diol;
    Reduced vitamin K3;
    Menadiol;
    2-methyl-1,4-naphthalenediol;
    Dihydrovitamin K3;
    2-Methyl-1,4-naphthalindiol;
    Vitamin K3H2;
    Reduced menadione;
    protrombrovit;
    2-Methyl-1,4-naphthohydroquinone;
    2-methyl-1,4-dihydroxynaphthalene;

    CAS No. 481-85-6
    Molecular Formula C11H10O2
    Molecular Weight 174.19600
    PSA 40.46000
    LogP 2.55940

    Properties

    Density 1.274g/cm3
    Boiling Point 391.6ºC at 760mmHg
    Flash Point 199.5ºC
    Refractive Index 1.697
    Vapor Pressure 1.08E-06mmHg at 25°C

    Synthesis Route

    menadionemenadiol
    1-ACETOXY-1,3-BUTADIENE+2-methylcyclohexa-2,5-diene-1,4-dionemenadiol
    2-Methyl-1-nitronaphthalenemenadiol

    Toxicity

    Exposure Route Type of Test Species Observed Dose/Duration Toxic Effects
    Oral LD50 - Lethal dose, 50 percent kill Rodent - mouse 30 mg/kg 1.Details of toxic effects not reported other than lethal dose value
    Intraperitoneal LDLo - Lowest published lethal dose Rodent - mouse 400 mg/kg 1.Details of toxic effects not reported other than lethal dose value
    Subcutaneous LDLo - Lowest published lethal dose Rodent - mouse 80 mg/kg 1.Behavioral-somnolence (general depressed activity)
    2.Lungs, Thorax, or Respiration-dyspnea

    Precursor

    2-methylcyclohexa-2,5-diene-1,4-dione
    Methylhydroquinone
    2-Methyl-1-nitronaphthalene
    1-ACETOXY-1,3-BUTADIENE

    Downstream Product

    2,3-dimethyl-1,2,3,4-tetrahydronaphthalene
    3,3'-Dimethyl-2,2'-methylenbis(1,4-naphthochinon)
    3,3'-Dimethyl-2,2'-ethylenbis(1,4-naphthochinon)
    menadione

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