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melphalan

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Origin: China

Cas No: 148-82-3

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 148-82-3 Formula: C13H18Cl2N2O2 Molecular Weight: 305.20000

    Description

    Antineoplastic.

    Basic Info

    Chemical Name melphalan
    Synonyms

    l-phenylalanine mustard;
    2-Amino-3-[4-[bis(2-chloroethyl)amino]phenyl]propanoic acid;
    Melphalan;
    3-(4-bis(2-chloroethyl)aminophenyl)-L-alanine;
    4-[bis(2-chloroethyl)amino]-l-phenylalanine;
    L-Phenylalanine, 4-[bis(2-chloroethyl)amino]-;

    CAS No. 148-82-3
    Molecular Formula C13H18Cl2N2O2
    Molecular Weight 305.20000
    PSA 66.56000
    LogP 2.62530

    Properties

    Appearance & Physical State Crystalline Solid
    Density 1.32 g/cm3
    Boiling Point 473.1ºC at 760 mmHg
    Melting Point 177ºC
    Flash Point 239.9ºC
    Storage Condition Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.

    Safety Info

    RTECS AY3675000
    Hazard Class 6.1(a)
    Safety Statements S53-S22-S36/37/39-S45
    HS Code 2922499990
    WGK Germany 3
    Packing Group II
    RIDADR UN 2811
    Risk Statements R45; R46; R26/27/28; R63
    Hazard Codes T+

    Synthesis Route

    methyl 2-amino-3-[4-[bis(2-chloroethyl)amino]phenyl]propanoate→melphalan
    N-Boc-4-[bis(2-hydroxyethyl)amino]-L-phenylalanine Methyl Ester→melphalan

    Precursor

    methyl 2-amino-3-[4-[bis(2-chloroethyl)amino]phenyl]propanoate
    N-Boc-4-[bis(2-hydroxyethyl)amino]-L-phenylalanine Methyl Ester

    Downstream Product

    methyl 2-amino-3-[4-[bis(2-chloroethyl)amino]phenyl]propanoate
    L-Alanine, 3-(p-[bis(2-chloroethyl)amino]phenyl)-N-formyl-

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