Home > All categories> Biochemicals and Pharmaceutical Chemicals> Pharmaceutical Impurities> megestrol acetate

megestrol acetate

Get Latest Price >

FOB Price contact us for price

Origin: China

Cas No: 595-33-5

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

Vendor:

Payment Terms:

Inquiry now

* Send an Inquiry to us

Add to wishlist

* Name your price
* Start order doesn't mean buying now

Products Specification
Product Description

Quick Details
CAS No.:
595-33-5
Other Names:
Megestrol Acetate
MF:
C23H30O4
EINECS No.:
209-864-5
Place of Origin:
Hubei, China
Type:
Auxiliaries and Other Medicinal Chemicals, Other
Grade Standard:
Medicine Grade
Usage:
Animal Pharmaceuticals
Brand Name:
Vanz
Model Number:
Megestrol Acetate
Purity:
99%
Name:
Megestrol acetate
Appearance:
powder
Color:
white
Shelf time:
2 years
Grade:
Phamaceutical Grade
Assay:
HPLC 99%
Storage:
Cool Dried Storage
Shelf life:
2 Years
Test Method:
HPLC Test
CAS:
595-33-5
Packaging&Delivery
Packaging Details
Bags or Drums
Port
Shanghai or Shenzhen
Products Description
Item Name

Megestrol Acetate
CAS NO.

595-33-5
Apparence

White Powder
Purity

99%
Certificate

GMP/ISO9001
Warranty

2 Years If Keep It Well

Property

CAS No.: 595-33-5 Formula: C24H32O4 Molecular Weight: 384.50800

Description

Megestrol acetate (INN, USAN, BAN, JAN) (abbreviated as MGA or MA, and sold mainly under the brand names Megace and Megace ES), also known as 17α-acetoxy-6-dehydro-6-methylprogesterone, is a steroidal progestin and progesterone derivative (specifically, a 17-hydroxylated progesterone) with predominantly progestational and antigonadotropic effects.
Though sometimes referred to simply as megestrol, it is important to clarify that megestrol acetate is not the same as megestrol, which is a closely related but different compound.

Basic Info

Chemical Name	megestrol acetate
Synonyms	[(8R,9S,10R,13S,14S,17R)-17-acetyl-6,10,13-trimethyl-3-oxo-2,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-17-yl] acetate; Megestrol acetate;
CAS No.	595-33-5
Molecular Formula	C24H32O4
Molecular Weight	384.50800
PSA	60.44000
LogP	4.57530

Properties

Appearance & Physical State	Crystalline Solid
Density	1.15g/cm3
Boiling Point	507.1ºC at 760mmHg
Melting Point	214ºC
Flash Point	218.5ºC
Refractive Index	11 ° (C=2, CHCl3)
Storage Condition	Refrigerator

Safety Info

RTECS	TU4075000
Safety Statements	S22-S24/25
WGK Germany	3
Risk Statements	R40; R48
Hazard Codes	Xn

Synthesis Route

[(8R,9S,10R,13S,14S,17R)-17-acetyl-10,13-dimethyl-6-methylidene-3-oxo-1,2,7,8,9,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-yl] acetate→megestrol acetate
Methoxymethyl acetate+(8R,9S,10R,13S,14S,17R)-17-acetyl-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate→megestrol acetate
medroxyprogesterone acetate→megestrol acetate

GC Analysis

Column type	Active phase	Temperature (°C)	Retention Index (I)	Temperature Control Method
Capillary	Ultra-2	-	2909.	temperature ramp

Precursor

3β,17α-dihydroxypregn-5-en-20-one 3-acetate
medroxyprogesterone acetate
Methoxymethyl acetate
[(8R,9S,10R,13S,14S,17R)-17-acetyl-10,13-dimethyl-6-methylidene-3-oxo-1,2,7,8,9,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-yl] acetate

Downstream Product

megestrol

Hot tags: megestrol acetate, China, manufacturers, suppliers, factory, wholesale, low price, high quality