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masitinib

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Origin: China

Cas No: 790299-79-5

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Quick Details
CAS No.:
790299-79-5
Other Names:
Masitinib
MF:
C28H30N6OS
EINECS No.:
N/A
Place of Origin:
Shaanxi, China
Type:
Auxiliaries and Other Medicinal Chemicals
Grade Standard:
Medicine Grade
Usage:
Animal Pharmaceuticals
Brand Name:
XABC, XABC Biotech CO.,LTD
Model Number:
XABC-09120
Purity:
99%
Product Name:
Masitinib
Appearance:
white powder
MW:
498.6424
Total Heavy Metals:
<10ppm
Test Method:
HPLC/UV
Standard:
USP EP JP etc.
Bacterial endoloxins:
<0.075EU/mg
Shelf life:
2 years
Packaging&Delivery
Packaging Details
Drum, Plastic Container, Vacuum Packed for High qualtiy Docetaxel intermediate 114915-14-9
Port
Qingdao Guangzhou etc

Property

CAS No.: 790299-79-5 Formula: C28H30N6OS Molecular Weight: 498.64200

Description

Masitinib controlled-release implant for treating solid neoplasm.

Basic Info

Chemical Name	masitinib
Synonyms	AB1010,Masivet,Masitinib; Masivet; 4-(4-methylpiperazin-1-ylmethyl)-N-[4-methyl-3-[4-(pyridin-3-yl)thiazol-2-ylamino]phenyl]benzamide; 4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-yl-1,3-thiazol-2-yl)amino]phenyl]benzamide; 4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-thiazolyl]amino]phenyl]benzamide; Masitinib; AB-1010;
CAS No.	790299-79-5
Molecular Formula	C28H30N6OS
Molecular Weight	498.64200
PSA	101.63000
LogP	5.27860

Properties

Density	1.281 g/cm3
Melting Point	90-95ºC
Refractive Index	1.682
Storage Condition	Refrigerator

Synthesis Route

4-methyl-N3-[4-(3-pyridyl)thiazol-2-yl]benzene-1,3-diamine+METHYL 4-[(4-METHYLPIPERAZIN-1-YL)METHYL]BENZOATE→masitinib
4-methyl-N3-[4-(3-pyridyl)thiazol-2-yl]benzene-1,3-diamine+4-[(4-methylpiperazin-1-yl)methyl]benzoyl chloride→masitinib
4-methyl-N3-[4-(3-pyridyl)thiazol-2-yl]benzene-1,3-diamine+4-(4-Methyl-1-piperazinylmethyl)benzoic Acid→masitinib

Precursor

4-(4-Methyl-1-piperazinylmethyl)benzoic Acid
4-methyl-N3-[4-(3-pyridyl)thiazol-2-yl]benzene-1,3-diamine
4-[(4-methylpiperazin-1-yl)methyl]benzoyl chloride
METHYL 4-[(4-METHYLPIPERAZIN-1-YL)METHYL]BENZOATE

Downstream Product

methanesulfonic acid,4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-yl-1,3-thiazol-2-yl)amino]phenyl]benzamide

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