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loxoprofen sodium hydrate

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Origin: China

Cas No: 80382-23-6

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 80382-23-6 Formula: C15H17NaO3 Molecular Weight: 268.28300

    Description

    A non-selective nonsteroidal anti-inflammatory drug (NSAID) that has been effective in reducing atherosclerosis in mice by reducing inflammation. It becomes active after metabolism in the body and inhibits the activation of cyclooxygenase.

    Basic Info

    Chemical Name loxoprofen sodium hydrate
    Synonyms

    Loxoprofen sodium;
    cs-600;
    loxoprofensodiumdihydrate;
    Loxoprofen sodiuM hydrate;
    LOXOPROFEN NA;
    SodiuM Loxoprofen;
    Loxonin;
    Unastin;
    sodium salt of Loxoprofen;

    CAS No. 80382-23-6
    Molecular Formula C15H17NaO3
    Molecular Weight 268.28300
    PSA 57.20000
    LogP 1.45170

    Properties

    Boiling Point 417.9ºCat 760 mmHg
    Flash Point 220.7ºC

    Safety Info

    HS Code 2918300090

    Synthesis Route

    loxoprofen→loxoprofen sodium hydrate

    Toxicity

    Exposure Route Type of Test Species Observed Dose/Duration Toxic Effects
    Oral LDLo - Lowest published lethal dose Human - man 857 ug/kg 1.Lungs, Thorax, or Respiration-bronchiolar constriction
    2.Lungs, Thorax, or Respiration-other changes
    Oral LD50 - Lethal dose, 50 percent kill Rodent - rat 145 mg/kg 1.Gastrointestinal-ulceration or bleeding from stomach
    2.Gastrointestinal-ulceration or bleeding from small intestine
    Intraperitoneal LD50 - Lethal dose, 50 percent kill Rodent - rat 245 mg/kg 1.Gastrointestinal-ulceration or bleeding from stomach
    2.Gastrointestinal-ulceration or bleeding from small intestine

    Precursor

    loxoprofen

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