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homatropine methylbromide

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Origin: China

Cas No: 80-49-9

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 80-49-9 Formula: C17H24BrNO3 Molecular Weight: 370.28100

    Description

    Homatropine methylbromide or Methylhomatropine bromide is a quaternary ammonium salt of methylhomatropine. Methylhomatropine is a peripherally acting anticholinergic medication that inhibits muscarinic acetylcholine receptors and thus the parasympathetic nervous system. Methylhomatropine does not cross the blood–brain barrier. Methylhomatropine is used, in addition to papaverine, as component of mild drugs that help "flush" the bile.

    Basic Info

    Chemical Name homatropine methylbromide
    Synonyms

    HOMATROPINE METHYL BROMIDE;
    8-Azoniabicyclo[3.2.1]octane, 3-[(hydroxyphenylacetyl)oxy]-8,8-dimethyl-, bromide, endo-(±)-;

    CAS No. 80-49-9
    Molecular Formula C17H24BrNO3
    Molecular Weight 370.28100
    PSA 46.53000
    LogP -1.00420

    Properties

    Density 1.21g/cm3
    Boiling Point 403.3ºC at 760 mmHg
    Melting Point 192ºC
    Flash Point 197.7ºC
    Refractive Index 1.588

    Safety Info

    RTECS MS9000000
    Safety Statements S22-S26-S36
    RIDADR UN 1544
    Risk Statements R20/21/22

    Toxicity

    Exposure Route Type of Test Species Observed Dose/Duration Toxic Effects
    Oral LD50 - Lethal dose, 50 percent kill Rodent - rat 1200 mg/kg 1.Details of toxic effects not reported other than lethal dose value
    Intraperitoneal LD50 - Lethal dose, 50 percent kill Rodent - rat 82 mg/kg 1.Details of toxic effects not reported other than lethal dose value
    Subcutaneous LD50 - Lethal dose, 50 percent kill Rodent - rat 800 mg/kg 1.Details of toxic effects not reported other than lethal dose value

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