Welcome to GlobalChemMall

ALL CATEGORIES
Categories
0
Wishlist
Home > Organofluorine Compounds> GW-0742
Picture of GW-0742

GW-0742

Get Latest Price >

FOB Price contact us for price

Origin: China

Cas No: 317318-84-6

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

Vendor:

Payment Terms:

Inquiry now

* Send an Inquiry to us

Add to wishlist

* Name your price
* Start order doesn't mean buying now

  • Products Specification
  • Product Description

  • Property

    CAS No.: 317318-84-6 Formula: C21H17F4NO3S2 Molecular Weight: 471.48800

    Description

    A small molecule agonist of the human Peroxisome Proliferator-Activated Recept δ (PPAR δ). It shows an EC50 of 1.1 nM against PPAR δ with 100-fold selectivity over the other human subtypes.

    Basic Info

    Chemical Name GW-0742
    Synonyms

    2-[4-[[2-[3-fluoro-4-(trifluoromethyl)phenyl]-4-methyl-1,3-thiazol-5-yl]methylsulfanyl]-2-methylphenoxy]acetic acid;
    Acetic acid, 2-[4-[[[2-[3-fluoro-4-(trifluoromethyl)phenyl]-4-methyl-5-thiazolyl]methyl]thio]-2-methylphenoxy]-;
    [4-[[[2-[3-fluoro-4-(trifluoromethyl)phenyl]-4-methyl-5-thiazolyl]methyl]thio]-2-methyl phenoxy]-acetic acid;
    GW-610742;
    GW-0742X;

    CAS No. 317318-84-6
    Molecular Formula C21H17F4NO3S2
    Molecular Weight 471.48800
    PSA 112.96000
    LogP 6.34050

    Properties

    Appearance & Physical State White to off-white solid
    Density 1.462g/cm3
    Boiling Point 591.476ºC at 760 mmHg
    Flash Point 311.514ºC
    Refractive Index 1.609
    Soluble DMSO: ≥ 34 mg/mL

    Synthesis Route

    4'-Hydroxy-3'-methylacetophenone→GW-0742
    methyl 2-(2-methyl-4-sulfanylphenoxy)acetate→GW-0742
    methyl 2-(4-hydroxy-2-methylphenoxy)acetate→GW-0742

    Precursor

    methyl 2-(4-acetyl-2-methylphenoxy)acetate
    methyl 2-(2-methyl-4-sulfanylphenoxy)acetate
    methyl 2-(4-hydroxy-2-methylphenoxy)acetate
    (4-acetoxy-2-methylphenoxy)acetic acid methyl ester

Hot tags: gw-0742, China, manufacturers, suppliers, factory, wholesale, low price, high quality
You may also like