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echinocandin B

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Origin: China

Cas No: 54651-05-7

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description
  • Quick Details

    CAS No.:
    54651-05-7
    Other Names:
    Echinocandin B
    MF:
    C34H51N7O15
    EINECS No.:
    NA
    Place of Origin:
    Shaanxi, China
    Type:
    Antibiotic and Antimicrobial Agents, Immune Function Agents
    Grade Standard:
    Medicine Grade
    Usage:
    Animal Pharmaceuticals
    Brand Name:
    Zelong
    Model Number:
    ZX20160805
    Purity:
    99%min
    Appearance:
    White Crystalline Powder
    Application:
    Pharmaceutical Raw Intermediates
    Package:
    Vacuum package
    Storage:
    Cool
    Delivery:
    Air cargo
    Shelf life:
    24 Months
    Lead time:
    1 day
    Manufacturer:
    Xi'an Zelong Biotech Co.,Ltd

    Packaging&Delivery

    Packaging Details
    Vacuum package (1-50g)
    Standard Drum 25KG
    Port
    Shanghai , Qingdao, Tianjin
    Lead Time:
    Quantity(Grams)1 - 9>9
    Est. Time(days)7To be negotiated
  • Property

    CAS No.: 54651-05-7 Formula: C52H81N7O16 Molecular Weight: 1060.24000

    Description

    Echinocandin B, a lipopeptide, is a naturally occurring cyclic hexapeptide with a linoleoyl side chain. It belongs to a class of antifungal agents called echinocandins, which inhibits the synthesis of glucan, a major component of the fungal cell wall, via noncompetitive inhibition of a crucial enzyme, β-(1,3)-D-glucan synthase. Echinocandin B is a fermentation product of Aspergillus nidulans and the closely related species, A. rugulosus; discovered in 1974 in A. nidulans var. echinulatus strain A 32204 in Germany, it was the first of the echinocandin class of antifungals.
    Echninocandin B can undergo deacylation (removal of the lipid side chain) by the action of a deacylase enzyme from the filamentous bacterium Actinoplanes utahensis, which catalyzes the cleavage of the linoleoyl side chain; in three subsequent synthetic steps, including a chemical reacylation, the antifungal drug anidulafungin is synthesized.

    Basic Info

    Chemical Name echinocandin B
    Synonyms

    CAS No. 54651-05-7
    Molecular Formula C52H81N7O16
    Molecular Weight 1060.24000
    PSA 368.19000
    LogP 0.25150

    Toxicity

    Exposure Route Type of Test Species Observed Dose/Duration Toxic Effects
    Intraperitoneal LD50 - Lethal dose, 50 percent kill Rodent - mouse 400 mg/kg 1.Details of toxic effects not reported other than lethal dose value

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