Welcome to GlobalChemMall

ALL CATEGORIES
Categories
0
Wishlist
Home > All categories> Biochemicals and Pharmaceutical Chemicals> Pharmaceutical Impurities> drospirenone
Picture of drospirenone

drospirenone

Get Latest Price >

FOB Price contact us for price

Origin: China

Cas No: 67392-87-4

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

Vendor:

Payment Terms:

Inquiry now

* Send an Inquiry to us

Add to wishlist

* Name your price
* Start order doesn't mean buying now

  • Products Specification
  • Product Description

  • Property

    CAS No.: 67392-87-4 Formula: C24H30O3 Molecular Weight: 366.49300

    Description

    Drospirenone (INN, USAN), also known as 1,2-dihydrospirorenone, is a steroidal progestin of the spirolactone group used in birth control pills and postmenopausal hormone replacement therapy pills.
    It is sold as a combined oral contraceptive under the brand names Yasmin (US, EU, Latin America), Jasmine (France), Yarina (Russia) in a dosage containing drospirenone 3mg/ethinylestradiol 30µg. In the United States, Bayer Schering released a pill based on Yasmin with the B vitamin folate (B9), which is marketed under the names Safyral and Beyaz.
    Worldwide it is also sold under the brand names Yaz and Yasminelle in a lower dosage containing drospirenone 3mg/ethinylestradiol 20µg.

    Basic Info

    Chemical Name drospirenone
    Synonyms

    Dorospirenone;
    arbolactone;
    ZK 3059;
    Drospirenona;
    Drospirenone;
    Drospirenon;
    6b,7b;
    dihydrospirorenone;

    CAS No. 67392-87-4
    Molecular Formula C24H30O3
    Molecular Weight 366.49300
    PSA 43.37000
    LogP 4.30590

    Properties

    Appearance & Physical State white to off-white crystalline powder
    Density 1.26 g/cm3
    Boiling Point 552.2ºC at 760 mmHg
    Melting Point 196-200ºC
    Flash Point 241.6ºC
    Refractive Index 1.61

    Safety Info

    HS Code 2937290090
    Caution Statement P201; P308 + P313
    Symbol GHS08
    Hazard Declaration H360
    Signal Word Danger

    Synthesis Route

    (2S,4aR,4bS,6aS,7S,7aS,8aS,8bS,8cR,9R)-9-(hydroxymethyl)-4a,6a-dimethyl-1,2,3,4,4a,4b,5,6,6a,7,7a,8,8a,8b,8c,9-hexadecahydrocyclopropa[4,5]cyclopenta[1,2-a]phenanthrene-2,7-diol→drospirenone
    →drospirenone
    →drospirenone

    Toxicity

    Exposure Route Type of Test Species Observed Dose/Duration Toxic Effects
    Subcutaneous TDLo - Lowest published toxic dose Rodent - rat 1200 ug/kg,female 1 day(s) pre-mating 1.Reproductive-Fertility-other measures of fertility

    Precursor

    (2S,4aR,4bS,6aS,7S,7aS,8aS,8bS,8cR,9R)-9-(hydroxymethyl)-4a,6a-dimethyl-1,2,3,4,4a,4b,5,6,6a,7,7a,8,8a,8b,8c,9-hexadecahydrocyclopropa[4,5]cyclopenta[1,2-a]phenanthrene-2,7-diol


    3β,5-dihydroxy-6β,7β;15β,16β-dimethylene-5β,17α-pregna-21,17-carbolactone

    Downstream Product

    6β,7β:15β,16β-dimethylene-1β-hydroxy-3-oxo-17α-pregn-4-ene-21,17-carbolactone
    6β,7β:15β,16β-dimethylene-2α-methyl-3-oxo-17α-pregn-4-ene-21,17-carbolactone
    6β,7β:15β,16β-dimethylene-12β-hydroxy-3-oxo-17α-pregn-4-ene-21,17-carbolactone
    6β,7β:15β,16β-dimethylene-2-methyl-3-oxo-17α-pregna-1,4-diene-21,17-carbolactone

Hot tags: drospirenone, China, manufacturers, suppliers, factory, wholesale, low price, high quality
Related Products
You may also like