Home > Chiral Compounds> ditert-butyl (2S,4S)-4-bromopyrrolidine-1,2-dicarboxylate

ditert-butyl (2S,4S)-4-bromopyrrolidine-1,2-dicarboxylate

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Origin: China

Cas No: 487048-27-1

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

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CAS No.: 487048-27-1 Formula: C14H24BrNO4 Molecular Weight: 350.24900

Basic Info

Chemical Name	ditert-butyl (2S,4S)-4-bromopyrrolidine-1,2-dicarboxylate
Synonyms	tert-butyl (2S,4S)-N-Boc-4-bromoprolinate; (2S)-N-Boc-cis-4-bromo-L-proline tert-butyl ester;
CAS No.	487048-27-1
Molecular Formula	C14H24BrNO4
Molecular Weight	350.24900
PSA	55.84000
LogP	3.03890

Properties

Density	1.304g/cm3
Boiling Point	373.6ºC at 760 mmHg
Flash Point	179.7ºC
Refractive Index	1.503

Synthesis Route

ditert-butyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate→ditert-butyl (2S,4S)-4-bromopyrrolidine-1,2-dicarboxylate
tert-butoxycarbonyl anhydride→ditert-butyl (2S,4S)-4-bromopyrrolidine-1,2-dicarboxylate
Boc-L-Hydroxyproline→ditert-butyl (2S,4S)-4-bromopyrrolidine-1,2-dicarboxylate

Precursor

ditert-butyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate
Boc-L-Hydroxyproline
4-hydroxy-L-proline
tert-butoxycarbonyl anhydride

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