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D-thyroxine

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Origin: China

Cas No: 51-49-0

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Product Description

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CAS No.: 51-49-0 Formula: C15H11I4NO4 Molecular Weight: 776.87000

Description

Dextrothyroxine (trade name Choloxin) saw research as a cholesterol-lowering drug but was pulled due to cardiac side-effects. It also increases hepatic lipase which in turn improves utilization of triglycerides, improving apolipoprotein E cholesterol particles.

Basic Info

Chemical Name	D-thyroxine
Synonyms	(2R)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoic acid; (R)-2-Amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)propanoic acid; D-Thyroxine; D-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-;
CAS No.	51-49-0
Molecular Formula	C15H11I4NO4
Molecular Weight	776.87000
PSA	92.78000
LogP	5.25760

Properties

Appearance & Physical State	Cream solid.
Density	2.635g/cm3
Boiling Point	576.3ºC at 760mmHg
Melting Point	225ºC
Flash Point	302.3ºC
Refractive Index	1.759
Stability	Stable under normal temperatures and pressures.
Storage Condition	2-8ºC

Safety Info

Safety Statements	S24/25
HS Code	2922509090
Risk Statements	R20/21/22
Hazard Codes	Xn

Synthesis Route

thyroxine→L-thyroxine+D-thyroxine
(2R)-2-amino-3-[4-(4-hydroxyphenoxy)-3,5-diiodophenyl]propanoic acid→D-thyroxine
3,5-DIIODO-DL-THYRONINE→D-thyroxine

Precursor

(2R)-2-amino-3-[4-(4-hydroxyphenoxy)-3,5-diiodophenyl]propanoic acid
N-formyl-3,5-diiodo-DL-thyronine
N-formyl-3,5-diiodo-L-thyronine
thyroxine

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