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bimatoprost

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Origin: China

Cas No: 155206-00-1

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description
  • Quick Details

    CAS No.:
    155206-00-1
    Other Names:
    Bimatoprost
    MF:
    C25H37NO4
    EINECS No.:
    no
    Place of Origin:
    Fujian, China
    Type:
    Ophthalmic drugs
    Grade Standard:
    Medicine Grade
    Brand Name:
    SINOWAY
    Model Number:
    99.5% by HPLC
    Purity:
    99.5% by HPLC
    Appearance:
    white powder
    Molecular structure:
    C25H37NO4
    Water:
    ≤1.0%
    CAS:
    155206-00-1
    15R-Bimatoprost::
    ≤0.30%
    Molecular weight:
    415.57
    Ter-Butylmethyl ether:
    5000ppm
    Specific rotation:
    [a]D20: +33.0°~+37.0°(C=1.0,CH3CN)
    purity:
    99.5% by HPLC
    Identification:
    HPLC retention time of sample complies with that of known sample

    Packaging&Delivery

    Packaging Details
    1g/bag, 10g/bag, or as your requirement.
    Port
    Beijing,Shanghai,Hangzhou,Nanjing,Ningbo
    Lead Time:
    Quantity(Grams)1 - 100>100
    Est. Time(days)7To be negotiated
  • Property

    CAS No.: 155206-00-1 Formula: C25H37NO4 Molecular Weight: 415.56600

    Description

    Bimatoprost (marketed in the US, Canada and Europe by Allergan, under the trade name Lumigan) is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. It reduces intraocular pressure (IOP) by increasing the outflow of aqueous fluid from the eyes. In December 2008, the indication to lengthen eyelashes was approved by the U.S. Food and Drug Administration (FDA); the cosmetic formulation of bimatoprost is sold as Latisse .

    Basic Info

    Chemical Name bimatoprost
    Synonyms

    BiMatoprost HOUSE STANDARD;
    BiMapnost;
    Prostamide;
    17-Phenyl-tri-norprostaglandin F2α-ethyl amide;
    LUMIGAN;
    Bimatoprost;

    CAS No. 155206-00-1
    Molecular Formula C25H37NO4
    Molecular Weight 415.56600
    PSA 89.79000
    LogP 3.53780

    Properties

    Appearance & Physical State crystalline solid
    Density 1.145 g/cm3
    Boiling Point 629.8ºC at 760 mmHg
    Flash Point 334.7ºC
    Refractive Index 1.591
    Storage Condition -20ºC
    Vapor Pressure 9.94E-17mmHg at 25°C

    Safety Info

    WGK Germany 3

    Synthesis Route

    (Z)-7-((1R,2R,3R,5S)-3-(tert-butyldimethylsilyloxy)-2-((S,E)-3-(tert-butyldimethylsilyloxy)-5-phenylpent-1-enyl)-5-hydroxycyclopentyl)-N-ethylhept-5-enamidebimatoprost
    propylamine+propan-2-yl (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]hept-5-enoatebimatoprost
    lactoltriol+(5-(ethylamino)-5-oxopentyl)triphenylphosphonium bromidebimatoprost

    Precursor

    propan-2-yl (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]hept-5-enoate
    (5-(ethylamino)-5-oxopentyl)triphenylphosphonium bromide
    (Z)-7-((1R,2R,3R,5S)-3-(tert-butyldimethylsilyloxy)-2-((S,E)-3-(tert-butyldimethylsilyloxy)-5-phenylpent-1-enyl)-5-hydroxycyclopentyl)-N-ethylhept-5-enamide
    lactoltriol

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