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Home > All categories> Biochemicals and Pharmaceutical Chemicals> Pharmaceutical Impurities> 4-hydroxy-N-[(E)-(5-nitrofuran-2-yl)methylideneamino]benzamide
Picture of 4-hydroxy-N-[(E)-(5-nitrofuran-2-yl)methylideneamino]benzamide

4-hydroxy-N-[(E)-(5-nitrofuran-2-yl)methylideneamino]benzamide

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Origin: China

Cas No: 965-52-6

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Quick Details

    CAS No.:
    965-52-6
    Other Names:
    Nifuroxazide
    MF:
    C12H9N3O5, C12H9N3O5
    EINECS No.:
    213-522-0
    Place of Origin:
    China
    Type:
    Pharmaceutical Intermediates
    Brand Name:
    HHSWN20011
    Model Number:
    HHSWN20011
    Application:
    Pharmaceutical intermediates
    Appearance:
    Bright yellow crystalline powder
    Product name:
    Nifuroxazide
    Color:
    Bright yellow crystalline powder
    CAS:
    965-52-6
    MW:
    281-283°C
    melting point:
    208-211 °C(lit.)
    Density:
    1.3877 (rough estimate)
    sample:
    available
    Boiling point:
    418.17°C (rough estimate)
    Refractive index:
    1.5700 (estimate)

    Packaging&Delivery

    Packaging Details
    Nifuroxazide
    BOTTLE Drum
    Port
    Shanghai/Qingdao port
    Lead Time:
    Quantity(Kilograms)1 - 1000>1000
    Est. Time(days)3To be negotiated

  • Property

    CAS No.: 965-52-6 Formula: C12H9N3O5 Molecular Weight: 275.21700

    Description

    Nifuroxazide (INN) is an oral nitrofuran antibiotic, patented since 1966 and used to treat colitis and diarrhea in humans and non-humans. It is sold under the brand names Ambatrol, Antinal, Bacifurane, Diafuryl, Pérabacticel (France), Antinal, Diax (Egypt), Nifrozid, Ercefuryl (Romania, Czech Republic, Russia), Erfuzide (Thailand), Endiex (Slovakia), Enterofuryl (Russia), Nifuroksazyd (Poland), Pentofuryl (Germany), Topron, Enterovid (Latin America), Eskapar (Mexico), Apazid (Morocco) and Septidiaryl. It is sold in capsule form and also as a suspension. The pharmaceutical group GlaxoSmithKline plc (Previously known as SmithKline Beecham) claims that nifuroxazide is highly effective and the consumers' group Healthy Skepticism says that GlaxoSmithKline's claims have no scientific support.

    Basic Info

    Chemical Name 4-hydroxy-N-[(E)-(5-nitrofuran-2-yl)methylideneamino]benzamide
    Synonyms

    Nifuroxazid;
    Nifuroxazidum;
    Nifuroxazide;
    Ercefuryl;
    Nifuroxazida;
    p-hydroxy-N'-(5-nitrofurfurylidene)benzhydrazide;
    Nifuroxazidum [INN-Latin];
    Diarlidan;
    Ercefurol;
    Dicoferin;

    CAS No. 965-52-6
    Molecular Formula C12H9N3O5
    Molecular Weight 275.21700
    PSA 120.65000
    LogP 2.57140

    Properties

    Appearance & Physical State Yellow solid
    Density 1.49 g/cm3
    Melting Point 281-283ºC
    Refractive Index 1.653
    Stability Stable at normal temperatures and pressures.
    Storage Condition Refrigerator, Under Inert Atmosphere

    Safety Info

    RTECS DH2528300
    HS Code 2928000090
    WGK Germany 3

    Synthesis Route

    (5-Nitrofuran-2-yl)methylene diacetate+4-Hydroxybenzhydrazide→4-hydroxy-N-[(E)-(5-nitrofuran-2-yl)methylideneamino]benzamide
    Methylparaben→4-hydroxy-N-[(E)-(5-nitrofuran-2-yl)methylideneamino]benzamide
    4-Hydroxybenzoic acid→4-hydroxy-N-[(E)-(5-nitrofuran-2-yl)methylideneamino]benzamide

    Precursor

    (5-Nitrofuran-2-yl)methylene diacetate
    4-Hydroxybenzoic acid
    Methylparaben
    4-Hydroxybenzhydrazide

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