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Picture of (3S,3'R,4'S,5'S,6'R)-5-[(4-ethylphenyl)methyl]-6'-(hydroxymethyl)spiro[1H-2-benzofuran-3,2'-oxane]-3',4',5'-triol

(3S,3'R,4'S,5'S,6'R)-5-[(4-ethylphenyl)methyl]-6'-(hydroxymethyl)spiro[1H-2-benzofuran-3,2'-oxane]-3',4',5'-triol

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Origin: China

Cas No: 903565-83-3

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

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    CAS No.: 903565-83-3 Formula: C22H26O6 Molecular Weight: 386.43800

    Description

    Tofogliflozin (USAN, codenamed CSG452) is an experimental drug for the treatment of diabetes mellitus and is being developed by Chugai Pharma in collaboration with Kowa and Sanofi. It is an inhibitor of subtype 2 sodium-glucose transport protein (SGLT2), which is responsible for at least 90% of the glucose reabsorption in the kidney. As of September 2012[update], the drug is in Phase III clinical trials.

    Basic Info

    Chemical Name (3S,3'R,4'S,5'S,6'R)-5-[(4-ethylphenyl)methyl]-6'-(hydroxymethyl)spiro[1H-2-benzofuran-3,2'-oxane]-3',4',5'-triol
    Synonyms

    Tofogliflozin anyhydrous;
    TOFOGLIFLOZIN;
    CSG 452;
    R-7201;
    Tofogliflozin [INN];

    CAS No. 903565-83-3
    Molecular Formula C22H26O6
    Molecular Weight 386.43800
    PSA 99.38000
    LogP 0.99660

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