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Home > All categories> Biochemicals and Pharmaceutical Chemicals> Pharmaceutical Impurities> (2S)-1-[4-(2-methoxyethyl)phenoxy]-3-(propan-2-ylamino)propan-2-ol
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(2S)-1-[4-(2-methoxyethyl)phenoxy]-3-(propan-2-ylamino)propan-2-ol

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Origin: China

Cas No: 81024-42-2

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 81024-42-2 Formula: C15H25NO3 Molecular Weight: 267.36400

    Description

    (S)-Enantiomer of Metoprolol. Antihypertensive; antianginal; antiarrhythmic (class II).

    Basic Info

    Chemical Name (2S)-1-[4-(2-methoxyethyl)phenoxy]-3-(propan-2-ylamino)propan-2-ol
    Synonyms

    l-Metoprolol;
    (S)-1-isopropylamino-3-[4-(2-metoxyethyl)phenoxy]propan-2-ol;
    (S)-(-)-Metoprolol;
    (2S)-1-isopropylamino-3-[p-(2-methoxyethyl)phenoxy]-2-propanol;
    (-)-Metoprolol;
    (S)-1-Isopropylamino-3-p-(2-methoxyethyl)phenoxy-propan-2-ol;
    (S)-1-(Isopropylamino)-3-(4-(2-methoxyethyl)phenoxy)propan-2-ol;

    CAS No. 81024-42-2
    Molecular Formula C15H25NO3
    Molecular Weight 267.36400
    PSA 50.72000
    LogP 2.00410

    Properties

    Density 1.033 g/cm3
    Boiling Point 398.6ºC at 760 mmHg
    Melting Point 41-43ºC
    Flash Point 194.9ºC
    Refractive Index 1.507
    Storage Condition -20ºC Freezer, Under Inert Atmosphere

    Safety Info

    HS Code 2922509090

    Synthesis Route

    (R)-1-O-methanesulfonyl-3-O-p-(2-methoxyethyl)phenylglyserol→(2S)-1-[4-(2-methoxyethyl)phenoxy]-3-(propan-2-ylamino)propan-2-ol
    2,2'-methylenedioxybis[(S)-N-isopropyl-3-p-(2-methoxyethyl)phenoxypropylamine]→(2S)-1-[4-(2-methoxyethyl)phenoxy]-3-(propan-2-ylamino)propan-2-ol
    Metoprolol→(2R)-1-[4-(2-methoxyethyl)phenoxy]-3-(propan-2-ylamino)propan-2-ol+(2S)-1-[4-(2-methoxyethyl)phenoxy]-3-(propan-2-ylamino)propan-2-ol

    Precursor

    2,2'-methylenedioxybis[(S)-N-isopropyl-3-p-(2-methoxyethyl)phenoxypropylamine]
    isopropylamine
    (R)-1-O-methanesulfonyl-3-O-p-(2-methoxyethyl)phenylglyserol
    (2S)-2-[[4-(2-methoxyethyl)phenoxy]methyl]oxirane

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