Home > Chiral Compounds> (2R,3S,5S)-5-(2-amino-6-chloropurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol

(2R,3S,5S)-5-(2-amino-6-chloropurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol

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Origin: China

Cas No: 120595-72-4

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Product Description

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CAS No.: 120595-72-4 Formula: C10H12ClN5O3 Molecular Weight: 285.68700

Basic Info

Chemical Name	(2R,3S,5S)-5-(2-amino-6-chloropurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol
Synonyms	2-amino-6-chloro-2'-deoxyguanosine; carbocyclic 2-amino-6-chloro-2'-deoxyadenosine; 2-AMINO-6-CHLOROPURINE-2`-DEOXYRIBOSIDE;
CAS No.	120595-72-4
Molecular Formula	C10H12ClN5O3
Molecular Weight	285.68700
PSA	119.31000
LogP	0.28380

Synthesis Route

6-chloroguanine→(2R,3S,5S)-5-(2-amino-6-chloropurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol
2-AMINO-6-CHLORO-9-(3,5-DI-O-(P-TOLUOYL)-β-D-2-DEOXYRIBOFURNANOSYL)PURINE→(2R,3S,5S)-5-(2-amino-6-chloropurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol
6-chloroguanine+thymidine→(2R,3S,5S)-5-(2-amino-6-chloropurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol

Precursor

3,5-DI-O-(P-TOLUYL)-2-DEOXY-D-RIBOFURANOSYL CHLORIDE
6-chloroguanine
thymidine
2-AMINO-6-CHLORO-9-(3,5-DI-O-(P-TOLUOYL)-β-D-2-DEOXYRIBOFURNANOSYL)PURINE

Downstream Product

2'-deoxyguanosine

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