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(2R)-pyrrolidine-2-carboxamide

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Origin: China

Cas No: 62937-45-5

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Product Description

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CAS No.: 62937-45-5 Formula: C5H10N2O Molecular Weight: 114.14600

Description

D-Prolinamide, can be used in the synthesis of proline derivatives as efficient organocatalysts for aldol reaction on water.

Basic Info

Chemical Name	(2R)-pyrrolidine-2-carboxamide
Synonyms	D-proline amide; H-(D)-Pro-NH2; (R)-Pyrrolidine-2-carboxamide; d-pro-nh2; h-d-pro-nh; D-Prolinamide;
CAS No.	62937-45-5
Molecular Formula	C5H10N2O
Molecular Weight	114.14600
PSA	55.12000
LogP	0.25280

Properties

Appearance & Physical State	White crystal powder
Density	1.106 g/cm3
Boiling Point	303.6ºC at 760 mmHg
Melting Point	95-97ºC
Flash Point	137.4ºC
Refractive Index	1.491
Storage Condition	-15ºC

Safety Info

Hazard Class	2.3
Safety Statements	S26; S36/37/39; S45
HS Code	2933990090
WGK Germany	3
RIDADR	UN 3304 2.3
Risk Statements	R34
Hazard Codes	C; T

Synthesis Route

benzyl (2R)-2-carbamoylpyrrolidine-1-carboxylate→(2R)-pyrrolidine-2-carboxamide
N-Benzyloxycarbonyl-D-proline→(2R)-pyrrolidine-2-carboxamide
D-proline→(2R)-pyrrolidine-2-carboxamide

Precursor

benzyl (2R)-2-carbamoylpyrrolidine-1-carboxylate
Boc-D-Proline amide
N-Benzyloxycarbonyl-D-proline
D-proline

Downstream Product

1-(Pyrrolidin-2-ylmethyl)pyrrolidine
pyrrolidin-2-ylmethylamine
2-methyl-1,2,3,4-tetrahydroquinoline

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