Home > Carbonyl Compounds> [2,8-bis(trifluoromethyl)quinolin-4-yl]-pyridin-2-ylmethanone

[2,8-bis(trifluoromethyl)quinolin-4-yl]-pyridin-2-ylmethanone

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Origin: China

Cas No: 35853-55-5

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 35853-55-5 Formula: C17H8F6N2O Molecular Weight: 370.24900

Basic Info

Chemical Name	[2,8-bis(trifluoromethyl)quinolin-4-yl]-pyridin-2-ylmethanone
Synonyms	bis[2,8-di(trifluoromethyl)quinolin-4-yl-2-pyridyl] ketone; pyridin-2-yl 2,8-bis(trifluoromethyl)-4-quinolyl ketone; QU020; 2-Pyridyl-2,8-bis(trifluoromethyl)-4-quinolylketone; (pyridin-2-yl)methanone; [2,8-bis(trifluoromethyl)-4-quinolinyl]-2-pyridinylmethanone; [2,8-bis(trifluoromethyl)quinolin-4-yl]-pyridin-2-yl-methanone; pyridin-2-yl-2,8-bis(trifluoromethyl)-4-quinolinemethanone;
CAS No.	35853-55-5
Molecular Formula	C17H8F6N2O
Molecular Weight	370.24900
PSA	42.85000
LogP	4.89840

Properties

Density	1.501g/cm3
Boiling Point	709.3ºC at 760mmHg
Flash Point	382.8ºC
Refractive Index	1.54

Safety Info

HS Code	2933990090
Symbol	GHS06
Hazard Declaration	H301; H413
Caution Statement	P301 + P310
Signal Word	Danger

Synthesis Route

2-[2,8-bis(trifluoromethyl)quinolin-4-yl]-2-pyridin-2-ylacetonitrile→[2,8-bis(trifluoromethyl)quinolin-4-yl]-pyridin-2-ylmethanone
α-Hydroxy-α-(2-pyridyl)-2,8-bis(trifluoromethyl)-4-quinolylacetonitrile→[2,8-bis(trifluoromethyl)quinolin-4-yl]-pyridin-2-ylmethanone
4-[(tert-butyldimethylsilyl)(2-pyridyl)methoxy]-2,8-bis(trifluoromethyl)quinoline→[2,8-bis(trifluoromethyl)quinolin-4-yl]-pyridin-2-ylmethanone+[2,8-bis(trifluoromethyl)quinolin-4-yl]-pyridin-2-ylmethanol

Precursor

2,8-bis(trifluoromethyl)-1H-quinolin-4-one
2-[2,8-bis(trifluoromethyl)quinolin-4-yl]-2-pyridin-2-ylacetonitrile
α-Hydroxy-α-(2-pyridyl)-2,8-bis(trifluoromethyl)-4-quinolylacetonitrile
4-[(tert-butyldimethylsilyl)(2-pyridyl)methoxy]-2,8-bis(trifluoromethyl)quinoline

Downstream Product

Mefloquine Hydrochloride

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