Home > Heterocyclic Compounds> 2',3'-O-Isopropylideneguanosine

2',3'-O-Isopropylideneguanosine

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Origin: China

Cas No: 362-76-5

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 362-76-5 Formula: C13H17N5O5 Molecular Weight: 323.30500

Description

A useful precursor for the preparation of nucleic acids.

Basic Info

Chemical Name	2',3'-O-Isopropylideneguanosine
Synonyms	2',3'-O-Isopropylidene-D-guanosine; 9-[(3aR,4R,6R,6aR)-4-(hydroxymethyl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-6-yl]-2-azanyl-3H-purin-6-one; 9-(2,3-O-Isopropylidene-β-D-ribofuranosyl)guanine; 2-amino-9-((3aR,4R,6R,6aR)-6-(hydroxymethyl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)-1H-purin-6(9H)-one; 2',3'-O-ISOPROPYLIDENE-GUANOSINE; 9-[(3aR,4R,6R,6aR)-4-(hydroxymethyl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-6-yl]-2-amino-3H-purin-6-one; 2',3'-O-(1-methylethylidene)-guanosine; 2',3'-O-Isopropylide; 2-amino-9-[(3aR,4R,6R,6aR)-6-(hydroxymethyl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl]-1,9-dihydro-6H-purin-6-one; 2',3'-ISOPROPYLIDENE-GUANOSINE; 2′,3′-O-Isopropylideneguanosine; 9-[(3aR,4R,6R,6aR)-2,2-dimethyl-4-methylol-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-6-yl]-2-amino-3H-purin-6-one; 2',3'-IPG;
CAS No.	362-76-5
Molecular Formula	C13H17N5O5
Molecular Weight	323.30500
PSA	137.51000
LogP	-0.30720

Properties

Appearance & Physical State	White Crystalline Solid
Density	1.93g/cm3
Boiling Point	647ºC at 760mmHg
Melting Point	296ºC
Flash Point	345.1ºC
Refractive Index	1.828

Safety Info

WGK Germany	3

Synthesis Route

guanosine+acetone→2',3'-O-Isopropylideneguanosine
guanosine+2,2-Dimethoxypropane→2',3'-O-Isopropylideneguanosine
acetone→2',3'-O-Isopropylideneguanosine

Precursor

acetone
guanosine
2-(Ethoxymethyl-amino)-9-((3aR,4R,6R,6aR)-6-hydroxymethyl-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl)-1,9-dihydro-purin-6-one
2,2-Dimethoxypropane

Downstream Product

guanosine
GDP
2-amino-9-[6-(azidomethyl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-4-yl]-3H-purin-6-one
GMP

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