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2-Methyl-4-(trifluoromethyl)thiazole-5-carboxylic acid

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Origin: China

Cas No: 117724-63-7

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

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CAS No.: 117724-63-7 Formula: C6H4F3NO2S Molecular Weight: 211.16200

Basic Info

Chemical Name	2-Methyl-4-(trifluoromethyl)thiazole-5-carboxylic acid
Synonyms	2-methyl-4-(trifluoromethyl)-1,3-thiazole-5-carboxylic acid;
CAS No.	117724-63-7
Molecular Formula	C6H4F3NO2S
Molecular Weight	211.16200
PSA	78.43000
LogP	2.16850

Properties

Density	1.57g/cm3
Boiling Point	285.5ºC at 760 mmHg
Flash Point	126.5ºC
Refractive Index	1.498
Vapor Pressure	0.0013mmHg at 25°C

Synthesis Route

Ethyl 2-chloro-4,4,4-trifluoroacetoacetate+thioacetamide→2-Methyl-4-(trifluoromethyl)thiazole-5-carboxylic acid
ethyl 2-methyl-4-(trifluoromethyl)-1,3-thiazole-5-carboxylate→2-Methyl-4-(trifluoromethyl)thiazole-5-carboxylic acid

Precursor

ethyl 2-methyl-4-(trifluoromethyl)-1,3-thiazole-5-carboxylate
thioacetamide
Ethyl 2-chloro-4,4,4-trifluoroacetoacetate

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