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Picture of 2-Methyl-2-propanyl (2S,4R)-4-{[dimethyl(2-methyl-2-propanyl)sily l]oxy}-2-(hydroxymethyl)-1-pyrrolidinecarboxylate

2-Methyl-2-propanyl (2S,4R)-4-{[dimethyl(2-methyl-2-propanyl)sily l]oxy}-2-(hydroxymethyl)-1-pyrrolidinecarboxylate

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Origin: China

Cas No: 114676-67-4

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description
  • Property

    CAS No.: 114676-67-4 Formula: C16H33NO4Si Molecular Weight: 331.52300

    Basic Info

    Chemical Name 2-Methyl-2-propanyl (2S,4R)-4-{[dimethyl(2-methyl-2-propanyl)sily l]oxy}-2-(hydroxymethyl)-1-pyrrolidinecarboxylate
    Synonyms

    Simvastatin acid ammonium;
    simvastatin hydroxy acid,ammonium salt;
    Simvastatin Acid Ammonium Salt;

    CAS No. 114676-67-4
    Molecular Formula C16H33NO4Si
    Molecular Weight 331.52300
    PSA 59.00000
    LogP 3.31640

    Synthesis Route

    (2S,4R)-1-Boc-2-methylcarboxylate-4-tert-butyldimethylsilyloxy-pyrrolidine2-Methyl-2-propanyl (2S,4R)-4-{[dimethyl(2-methyl-2-propanyl)sily l]oxy}-2-(hydroxymethyl)-1-pyrrolidinecarboxylate
    1-tert-butyl 2-ethyl (2S,4R)-4-{[tert-butyl (dimethyl)silyl]oxy} pyrrolidine-1,2-dicarboxylate2-Methyl-2-propanyl (2S,4R)-4-{[dimethyl(2-methyl-2-propanyl)sily l]oxy}-2-(hydroxymethyl)-1-pyrrolidinecarboxylate
    tert-butoxycarbonyl anhydride2-Methyl-2-propanyl (2S,4R)-4-{[dimethyl(2-methyl-2-propanyl)sily l]oxy}-2-(hydroxymethyl)-1-pyrrolidinecarboxylate

    Precursor

    1-tert-butyl 2-ethyl (2S,4R)-4-{[tert-butyl (dimethyl)silyl]oxy} pyrrolidine-1,2-dicarboxylate
    tert-butyldimethylsilyl chloride
    tert-butoxycarbonyl anhydride
    (2S,4R)-1-Boc-2-methylcarboxylate-4-tert-butyldimethylsilyloxy-pyrrolidine

    Downstream Product

    (2R,4R)-N-Boc-4-hydroxy-2-methylpyrrolidine

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