Home > All categories> Biochemicals and Pharmaceutical Chemicals> Pharmaceutical Impurities> 2-butyl-5-chloro-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carboxylic acid

2-butyl-5-chloro-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carboxylic acid

Get Latest Price >

FOB Price contact us for price

Origin: China

Cas No: 124750-92-1

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

Vendor:

Payment Terms:

Inquiry now

* Send an Inquiry to us

Add to wishlist

* Name your price
* Start order doesn't mean buying now

Products Specification
Product Description

Quick Details
Place of Origin:
Zhejiang, China
Brand Name:
Amadis Chemical
Model Number:
124750-92-1
CAS NO:
124750-92-1
Synonyms:
EXP-3174
Test Method:
HNMR/CNMR/FNMR,HPLC/GC,MS
Safety:
COA,SDS,BSE/TSE
Purity:
95%-99%
Certificate:
ISO9001-2008
Purpose:
All chemicals are for R&D use only
Storage Condition:
Store in a tightly closed container,in a cool and dry place
Packaging&Delivery
Packaging Details
Professional packaging can be according the customers'requirment.
Port
Shanghai

Property

CAS No.: 124750-92-1 Formula: C22H21ClN6O2 Molecular Weight: 436.89400

Description

A metabolite of Losartan.

Basic Info

Chemical Name	2-butyl-5-chloro-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carboxylic acid
Synonyms	2-n-butyl-5-chloro-3-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3H-imidazole-4-carboxylic acid; E-3174; Losartan carboxylic acid; 1H-Imidazole-5-carboxylic acid,2-butyl-4-chloro-1-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl); Exp3174;
CAS No.	124750-92-1
Molecular Formula	C22H21ClN6O2
Molecular Weight	436.89400
PSA	109.58000
LogP	4.47270

Properties

Appearance & Physical State	Light-Yellow Solid
Density	1.41g/cm3
Boiling Point	707.8ºC at 760mmHg
Melting Point	130-132ºC
Flash Point	381.8ºC
Refractive Index	1.695
Vapor Pressure	5.04E-21mmHg at 25°C

Synthesis Route

Losartan potassium→2-butyl-5-chloro-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carboxylic acid
losartan→2-butyl-5-chloro-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carboxylic acid
Losartan potassium→2-butyl-5-chloro-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carbaldehyde+2-butyl-5-chloro-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carboxylic acid

Toxicity

Exposure Route	Type of Test	Species Observed	Dose/Duration	Toxic Effects
Intraperitoneal	LD50 - Lethal dose, 50 percent kill	Rodent - mouse	441 mg/kg	1.Sense Organs and Special Senses (Eye)-mydriasis (pupillary dilation) 2.Behavioral-tremor 3.Lungs, Thorax, or Respiration-respiratory depression

Precursor

Losartan potassium
losartan

Downstream Product

2-butyl-4-chloro-1-[(2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl]-1H-imidazole-5-carboxylic acid 2-(methylsulfonylthio)ethyl ester
1,3-dicyclohexylurea
2-butyl-5-chloro-3-[[4-[2-(1-trityltetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carboxylic acid
2-butyl-4-chloro-1-[(2'-(1H-tetrazol-5-yl) (1,1'-biphenyl)-4-yl)methyl]-1H-imidazole-5-carboxylic acid 4-(3H-1,2-dithiole-3-thione-5-yl)-phenyl ester

Hot tags: 2-butyl-5-chloro-3-[[4-[2-(2h-tetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carboxylic acid, China, manufacturers, suppliers, factory, wholesale, low price, high quality