Home > Organophosphorus Compounds> [2-[(4S)-5,5-dimethyl-4-propan-2-yl-4H-1,3-oxazol-2-yl]phenyl]-diphenylphosphane

[2-[(4S)-5,5-dimethyl-4-propan-2-yl-4H-1,3-oxazol-2-yl]phenyl]-diphenylphosphane

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Origin: China

Cas No: 1152313-76-2

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 1152313-76-2 Formula: C26H28NOP Molecular Weight: 401.48000

Basic Info

Chemical Name	[2-[(4S)-5,5-dimethyl-4-propan-2-yl-4H-1,3-oxazol-2-yl]phenyl]-diphenylphosphane
Synonyms	(S)-5,5-(dimethyl)-i-Pr-PHOX; (4S)-2-[2-(diphenylphosphino)phenyl]-4,5-dihydro-5,5-dimethyl-4-(1-methylethyl)-oxazole; (S)-2-(2-(Diphenylphosphino)phenyl)-4-isopropyl-5,5-dimethyl-4,5-dihydrooxazole;
CAS No.	1152313-76-2
Molecular Formula	C26H28NOP
Molecular Weight	401.48000
PSA	35.18000
LogP	4.46040

Synthesis Route

(S)-2-(2-fluorophenyl)-4-isopropyl-5,5-dimethyl-4,5-dihydrooxazole+Diphenylphosphine→[2-[(4S)-5,5-dimethyl-4-propan-2-yl-4H-1,3-oxazol-2-yl]phenyl]-diphenylphosphane
(S)-2-(2-bromophenyl)-4-isopropyl-5,5-dimethyl-4,5-dihydrooxazole+Diphenylphosphine→[2-[(4S)-5,5-dimethyl-4-propan-2-yl-4H-1,3-oxazol-2-yl]phenyl]-diphenylphosphane
L-valine→[2-[(4S)-5,5-dimethyl-4-propan-2-yl-4H-1,3-oxazol-2-yl]phenyl]-diphenylphosphane

Precursor

(S)-2-(2-fluorophenyl)-4-isopropyl-5,5-dimethyl-4,5-dihydrooxazole
Diphenylphosphine
methyl (2S)-3-methyl-2-[(2-methylpropan-2-yl)oxycarbonylamino]butanoate
L-valine

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