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17β-Hydroxy Exemestane

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Origin: China

Cas No: 122370-91-6

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 122370-91-6 Formula: C20H26O2 Molecular Weight: 298.41900

Description

A metabolite of Exemestane; exerts biological effects as an androgen.

Basic Info

Chemical Name	17β-Hydroxy Exemestane
Synonyms	(8R,9S,10R,13S,14S,17S)-17-hydroxy-10,13-dimethyl-6-methylidene-8,9,11,12,14,15,16,17-octahydro-7H-cyclopenta[a]phenanthren-3-one;
CAS No.	122370-91-6
Molecular Formula	C20H26O2
Molecular Weight	298.41900
PSA	37.30000
LogP	3.82130

Properties

Density	1.14
Boiling Point	454.94ºC at 760 mmHg
Melting Point	134-136ºC
Refractive Index	1.581

Synthesis Route

17β-hydroxy-6-methyleneandrost-4-en-3-one→17β-Hydroxy Exemestane
6-methyleneandrosta-1,4-dien-3-one 17β-acetate→17β-Hydroxy Exemestane
Formaldehyde+boldenone→17β-Hydroxy Exemestane

Precursor

17β-hydroxy-6-methyleneandrost-4-en-3-one
boldenone
Formaldehyde
6-methyleneandrosta-1,4-dien-3-one 17β-acetate

Downstream Product

Spiro[androsta-1,4-diene-6,2'-oxirane]-3,17-dione
exemestane

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