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17α-(3-hydroxypropyl)-6β,7β,15β,16β-dimethylen-5β-androstan-5,17β-ol-3-one

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Origin: China

Cas No: 1357252-81-3

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Product Description

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CAS No.: 1357252-81-3 Formula: C24H36O4 Molecular Weight: 388.54000

Description

5-Hydroxy Drospirenone Ring-opened Alcohol Impurity is an impurity of Drospirenone.

Basic Info

Chemical Name	17α-(3-hydroxypropyl)-6β,7β,15β,16β-dimethylen-5β-androstan-5,17β-ol-3-one
Synonyms	5\|A-Hydroxy Drospirenone Ring-opened Alcohol Impurity; 17\|A-[3-Hydroxypropyl]-6\|A,7\|A:15\|A,16\|A-dimethylen-5\|A-androstan-5,17\|A-ol-3-one; (5R,6R,7R,8R,9S,10R,13S,14S,15S,16S,17S)-Octadecahydro-5,17-dihydroxy-17-(3-hydroxypropyl)-10,13-dimethyl-3H-dicyclopropa[6,7:15,16]cyclopenta[a]phenanthren-3-one;
CAS No.	1357252-81-3
Molecular Formula	C24H36O4
Molecular Weight	388.54000
PSA	77.76000
LogP	2.92850

Synthesis Route

17α-[3-(tert-butyldimethylsilanyloxy)propyl]-6β,7β,15β,16β-dimethylen-5β-androstan-3β,5,17β-ol-3-one→17α-(3-hydroxypropyl)-6β,7β,15β,16β-dimethylen-5β-androstan-5,17β-ol-3-one
17α-[3-(tert-butyldimethylsilanyloxy)propyl]-6β,7β,15β,16β-dimethylen-5β-androstane-3β,5,17β-triol→17α-(3-hydroxypropyl)-6β,7β,15β,16β-dimethylen-5β-androstan-5,17β-ol-3-one

Precursor

17α-[3-(tert-butyldimethylsilanyloxy)propyl]-6β,7β,15β,16β-dimethylen-5β-androstan-3β,5,17β-ol-3-one
17α-[3-(tert-butyldimethylsilanyloxy)propyl]-6β,7β,15β,16β-dimethylen-5β-androstane-3β,5,17β-triol

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